Understanding microRNA-mediated gene regulatory networks through mathematical modelling
The discovery of microRNAs (miRNAs) has added a new player to the regulation of gene
expression. With the increasing number of molecular species involved in gene regulatory …
expression. With the increasing number of molecular species involved in gene regulatory …
Highlights of recent developments and trends in cancer nanotechnology research—View from NCI Alliance for Nanotechnology in Cancer
LC Hull, D Farrell, P Grodzinski - Biotechnology advances, 2014 - Elsevier
Although the incidence of cancer and cancer related deaths in the United States has
decreased over the past two decades due to improvements in early detection and treatment …
decreased over the past two decades due to improvements in early detection and treatment …
MicroRNA-146a: a key regulator of astrocyte-mediated inflammatory response
A Iyer, E Zurolo, A Prabowo, K Fluiter, WGM Spliet… - 2012 - journals.plos.org
Increasing evidence supports the involvement of microRNAs (miRNA) in the regulation of
inflammation in human neurological disorders. In the present study we investigated the role …
inflammation in human neurological disorders. In the present study we investigated the role …
Scanometric microRNA array profiling of prostate cancer markers using spherical nucleic acid–gold nanoparticle conjugates
AH Alhasan, DY Kim, WL Daniel, E Watson… - Analytical …, 2012 - ACS Publications
We report the development of a novel Scanometric MicroRNA (Scano-miR) platform for the
detection of relatively low abundance miRNAs with high specificity and reproducibility. The …
detection of relatively low abundance miRNAs with high specificity and reproducibility. The …
Loss of SHIP-1 protein expression in high-risk myelodysplastic syndromes is associated with miR-210 and miR-155
The myelodysplastic syndromes (MDSs) comprise a group of disorders characterized by
multistage progression from cytopenias to acute myeloid leukemia (AML). They display …
multistage progression from cytopenias to acute myeloid leukemia (AML). They display …
MicroRNA-Regulated Networks: The Perfect Storm for Classical Molecular Biology, the Ideal Scenario for Systems Biology
MicroRNAs (miRNAs) are involved in many regulatory pathways some of which are complex
networks enriched in regulatory motifs like positive or negative feedback loops or coherent …
networks enriched in regulatory motifs like positive or negative feedback loops or coherent …
Regulation of coagulation factor XI expression by microRNAs in the human liver
S Salloum-Asfar, R Teruel-Montoya, AB Arroyo… - PloS one, 2014 - journals.plos.org
High levels of factor XI (FXI) increase the risk of thromboembolic disease. However, the
genetic and environmental factors regulating FXI expression are still largely unknown. The …
genetic and environmental factors regulating FXI expression are still largely unknown. The …
MicroRNA expression profiles in metastatic and non-metastatic giant cell tumor of bone
N Mosakhani, L Pazzaglia, MS Benassi, I Borze… - 2013 - digitum.um.es
Giant cell tumor of bone (GCTB) is a skeletal neoplasm, a locally aggressive tumor that
occasionally metastasizes to the lungs. To identify novel biomarkers associated with GCTB …
occasionally metastasizes to the lungs. To identify novel biomarkers associated with GCTB …
The RNA world in the 21st century—a systems approach to finding non-coding keys to clinical questions
There was evidence that RNAs are a functionally rich class of molecules not only since the
arrival of the next-generation sequencing technology. Non-coding RNAs (ncRNA) could be …
arrival of the next-generation sequencing technology. Non-coding RNAs (ncRNA) could be …
An evolutionarily biased distribution of miRNA sites toward regulatory genes with high promoter-driven intrinsic transcriptional noise
Background miRNAs are a major class of regulators of gene expression in metazoans. By
targeting cognate mRNAs, miRNAs are involved in regulating most, if not all, biological …
targeting cognate mRNAs, miRNAs are involved in regulating most, if not all, biological …