Live to fight another day: The bacterial nucleoid under stress

AM Walker, EA Abbondanzieri… - Molecular …, 2024 - Wiley Online Library
The bacterial chromosome is both highly supercoiled and bound by an ensemble of proteins
and RNA, causing the DNA to form a compact structure termed the nucleoid. The nucleoid …

Rok from B. subtilis: Bridging genome structure and transcription regulation

AM Erkelens, B van Erp, WJJ Meijer… - Molecular …, 2024 - Wiley Online Library
Bacterial genomes are folded and organized into compact yet dynamic structures, called
nucleoids. Nucleoid orchestration involves many factors at multiple length scales, such as …

Expanding the genetic toolbox for the obligate human pathogen Streptococcus pyogenes

N Lautenschlaeger, K Schmidt, C Schiffer, TF Wulff… - bioRxiv, 2024 - biorxiv.org
Genetic tools form the basis for the study of molecular mechanisms. Despite many recent
advances in the field of genetic engineering in bacteria, genetic toolsets remain scarce for …