Protein kinase C (PKC) is a family of phospholipid‐dependent serine/threonine kinases,
which can be further classified into three PKC isozymes subfamilies: conventional or classic …

Background The gold standard endpoint in randomised trials of locally advanced head and
neck squamous-cell carcinoma (HNSCC) is overall survival. Our objective was to study …

Dent Clin N Am 62 (2018) 29–46 http://dx. doi. org/10.1016/j. cden. 2017.08. 002 dental.
theclinics. com 0011-8532/18/© 2017 Elsevier Inc. All rights reserved. diagnosed cancer …

Head and neck cancer is the sixth most common cancer worldwide. At present, globally
about 650,000 new cases of squamous cell carcinoma of the head and neck (SCCHN) are …

Oral squamous cell carcinoma (OSCC) of head and neck is associated with high morbidity
and mortality in both Western and Asian countries. Several risk factors for the development …

Oral carcinogenesis is a complex and multifactorial process that involves cumulative genetic
and molecular alterations, leading to uncontrolled cell proliferation, impaired DNA repair …

Oral cavity squamous cell carcinoma (OSCC) is considered one of the most aggressive
subtypes of cancer. Anti-CD44 monoclonal antibodies (mAb) are a potential therapy against …

Head and neck squamous cell carcinoma (HNSCC) is driven by cancer-initiating cells (CIC),
but their maintenance mechanisms are obscure. For hematopoietic stem cells, low levels of …

Head and neck cancer is disfiguring and deadly, and contemporary treatment has fallen
short in terms of morbidity and mortality. The rich immune infiltrate within these tumors …

Background Recently, studies indicated that cancer stem cell plays a key role in cancer
development and progression. However, the role of cancer stem cell has not been well …