The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …

Blood travels throughout the body in an extensive network of vessels–arteries, veins and
capillaries. This vascular network is not static, but instead dynamically remodels in response …

Developing personalized diagnostic strategies and targeted treatments requires a deep
understanding of disease biology and the ability to dissect the relationship between …

The age-adjusted prevalence of peripheral arterial disease in the US population was
estimated to approach 12% in 1985, and as the population ages, the overall population …

Several cytokine families have roles in the development, maintenance, and remodeling of
the microcirculation. Of these, the vascular endothelial growth factor (VEGF) family is one of …

To improve understanding of microvascular O2 transport, theoretical modeling has been
pursued for many years. The large number of studies in this area attests to the complexities …

This article aims to promote integration of angiogenesis-related models, both integration of
the work described herein and many other existing and future models. Integration of …

Background Angiogenesis is a process by which new capillaries are formed from pre-
existing blood vessels in physiological (eg, exercise, wound healing) or pathological (eg …

Over the past two decades, a number of mathematical and computational models have been
developed to study different aspects of angiogenesis that span the spatial and temporal …

In recent years, MSC s have emerged as a promising therapeutic cell type in regenerative
medicine. They hold great promise for treating cardiovascular diseases, such as myocardial …