Strategies for prevention and treatment of Trichomonas vaginalis infections

K Bouchemal, C Bories, PM Loiseau - Clinical microbiology …, 2017 - Am Soc Microbiol
The last estimated annual incidence of Trichomonas vaginalis worldwide exceeds that of
chlamydia and gonorrhea combined. This critical review updates the state of the art on …

Thirty years with cyclodextrins

D Duchene, A Bochot - International journal of pharmaceutics, 2016 - Elsevier
This paper reviews the work carried out on cyclodextrins during some thirty years at the
Institut Galien Paris-Sud, UMR CNRS 8612, Université Paris-Sud. It represents the normal …

Self-assembly of cyclodextrins and their complexes in aqueous solutions

A Ryzhakov, T Do Thi, J Stappaerts, L Bertoletti… - Journal of …, 2016 - Elsevier
Cyclodextrins (CDs) are enabling pharmaceutical excipients that can be found in numerous
pharmaceutical products worldwide. Because of their favorable toxicologic profiles, CDs are …

Solubility enhancement of mefenamic acid by inclusion complex with β-cyclodextrin: in silico modelling, formulation, characterisation, and in vitro studies

D Sid, M Baitiche, Z Elbahri, F Djerboua… - Journal of enzyme …, 2021 - Taylor & Francis
The aim of this study was to prepare and characterise inclusion complexes of a low water-
soluble drug, mefenamic acid (MA), with β-cyclodextrin (β-CD). First, the phase solubility …

[HTML][HTML] Dissolution/permeation of albendazole in the presence of cyclodextrin and bile salts: a mechanistic in vitro study into factors governing oral bioavailability

JB Eriksen, SB Christensen, A Bauer-Brandl… - Journal of …, 2022 - Elsevier
We aimed to understand the impact of the interplay between bile salts and cyclodextrins on
the dissolution-permeation of poorly soluble drug compounds with a moderate-strong …

The Use of Cyclodextrin Inclusion Complexes to Increase the Solubility and Pharmacokinetic Profile of Albendazole

Y Ding, Z Zhang, C Ding, S Xu, Z Xu - Molecules, 2023 - mdpi.com
Albendazole is the preferred deworming drug and has strong insecticidal effects on human
and animal helminth parasites, showing remarkable activity against hepatocellular …

Albendazole-lipid nanocapsules: Optimization, characterization and chemoprophylactic efficacy in mice infected with Echinococcus granulosus

GVU Gamboa, PE Pensel, MC Elissondo… - Experimental …, 2019 - Elsevier
Cystic echinococcosis (CE), which is caused during the metacestode larval stage of
Echinococcus granulosus, is a life-threatening disease and is very difficult to treat. At …

Inclusion complexes and self-assembled cyclodextrin aggregates for increasing the solubility of benzimidazoles

LNC Rodrigues, ACM Tavares, BT Ferreira… - Brazilian Journal of …, 2019 - SciELO Brasil
Albendazole and fenbendazole are imidazole derivatives that exhibit broad spectrum activity
against parasites, but the low solubility of these drugs considerably reduces their …

Structural and energetic investigation on the host/guest inclusion process of benzyl isothiocyanate into β-cyclodextrin using dispersion-corrected DFT calculations

A Bouhadiba, S Rahali, Y Belhocine, H Allal… - Carbohydrate …, 2020 - Elsevier
The formation of host-guest complex between benzyl isothiocyanate (BITC) and β-
cyclodextrin (β-CD) was studied using dispersion-corrected density functional theory …

Exploring the preparation of albendazole-loaded chitosan-tripolyphosphate nanoparticles

BS Kang, SE Lee, CL Ng, JK Kim, JS Park - Materials, 2015 - mdpi.com
The objective of this study was to improve the solubility of albendazole and optimize the
preparation of an oral nanoparticle formulation, using β-cyclodextrin (βCD) and chitosan …