Topical capsaicin formulations are used for pain management. Safety and modest efficacy of
low-concentration capsaicin formulations, which require repeated daily self-administration …

Capsaicin is a widespread spice known for its analgesic qualities. Although a
comprehensive body of evidence suggests pleiotropic benefits of capsaicin, including anti …

Introduction Neuropathic pain (NP) is caused by a lesion or disease of the somatosensory
system, which can severely impact patients' quality of life. The current-approved treatments …

Methods: In this randomized, double-blind, controlled study, patients with pain due to HIV-
associated distal sensory polyneuropathy received a single 30-minute or 60-minute …

Objectives: Analyses of integrated data from 4 controlled postherpetic neuralgia studies
evaluated the effect of NGX-4010, a capsaicin 8% patch, administered alone or together with …

Capsaicin dermal patch is an adhesive patch containing a high concentration (8% w/w) of
synthetic capsaicin. It is indicated in the EU for the treatment of peripheral neuropathic pain …

Objective To investigate the response of patients with peripheral neuropathic pain (PNP) to
capsaicin 8% patch treatment in a clinical setting. Design Retrospective analysis. Setting …

Transdermal therapeutic systems (TTSs) enable convenient dosing in drug therapy.
Modified silicone-polymer-based patches are well-controlled and cost-effective matrix …

Background HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently
reported neurologic complication associated with HIV infection. NGX-4010 is a capsaicin 8 …

AIMS: To assess efficacy, safety, and tolerability of NGX-4010, capsaicin 8% patch, in
patients with peripheral neuropathic pain. METHODS: This open-label, uncontrolled, 12 …