Emerging roles of mesenchymal stem/stromal-cell-derived extracellular vesicles in cancer therapy

A Nicodemou, S Bernátová, M Čeháková, Ľ Danišovič - Pharmaceutics, 2023 - mdpi.com
Despite the tremendous efforts of many researchers and clinicians, cancer remains the
second leading cause of mortality worldwide. Mesenchymal stem/stromal cells (MSCs) are …

Cytocompatible triblock copolymers with controlled microstructure enabling orthogonally functionalized bio-polymer conjugates

K Halama, MTY Lin, A Schaffer, M Foith… - …, 2024 - ACS Publications
α, ω-Functionalized block copolymers create various opportunities across myriads of
applications such as linkers for targeted drug delivery systems. Combining them with the …

[HTML][HTML] Exosomes: Membrane-associated proteins, challenges and perspectives

N Palomar-Alonso, M Lee, M Kim - Biochemistry and Biophysics Reports, 2024 - Elsevier
Membrane proteins determine the precise function of each membrane and, therefore, the
function of each cell type. These proteins essential roles in cell physiology, participating in …

Advancements in 5-Fluorouracil-Loaded Liposomal Nanosystems: A Comprehensive Review on Recent Innovations in Nanomedicine for Cancer Therapy

MS Ali, SK Jha, G Gupta, A Alsayari, S Wahab… - Journal of Drug Delivery …, 2024 - Elsevier
The increasing worldwide cancer prevalence is a result of population aging and expansion
and changes in individuals' exposure to risk factors, many of which are linked to …

Co-delivery of simvastatin and microRNA-21 through liposome could accelerates the wound healing process

M Kiani, F Moraffah, F Khonsari, B Kharazian… - Biomaterials …, 2023 - Elsevier
The gene delivery approach, mainly microRNAs (miRNA) as key wound healing mediators,
has recently received extensive attention. MicroRNA-21 (miR-21) has strongly impacted …

Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions

H Suzuki, A Adler, T Huang, A Kuramochi… - … and Technology of …, 2022 - Taylor & Francis
Liposome surface coating has been studied to avoid the immunological responses caused
by the complement system, and alternative materials to poly (ethylene glycol)(PEG) have …

The optimization design of macrophage membrane camouflaging liposomes for alleviating ischemic stroke injury through intranasal delivery

T Liu, Y Wang, M Zhang, J Zhang, N Kang… - International Journal of …, 2024 - mdpi.com
Ischemic stroke is associated with a high mortality rate, and effective treatment strategies are
currently lacking. In this study, we aimed to develop a novel nano delivery system to treat …

A Dual Functional Bioinspired Lubricant for Osteoarthritis Treatment and Potential Prevention

R Yan, H Yang, Y Liu, Y Wang, S Liu… - ACS Applied Materials …, 2024 - ACS Publications
Osteoarthritis (OA), primarily characterized by the deterioration of articular cartilage, is a
highly prevalent joint-disabling disease. The pathological onset and progression of OA are …

Mannosylated-chitosan-coated andrographolide nanoliposomes for the treatment of hepatitis: in vitro and in vivo evaluations

SP Metkar, G Fernandes, AN Nikam, S Soman… - Membranes, 2023 - mdpi.com
A key diterpene lactone of Andrographis paniculata, ie, andrographolide (AG), exhibits a
variety of physiological properties, including hepatoprotection. The limited solubility, short …

Highly Robust Multilamellar Lipid Vesicles Generated through Intervesicular Self-Assembly Mediated by Hydrolyzed Collagen Peptides

BI Koo, RT Rahman, J Jang, DJ Lee, JB Lee… - …, 2023 - ACS Publications
Despite the well-known advantages of lipid vesicles for drug and gene delivery, structural
instability limits their practical applications and requires strictly regulated conditions for …