Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

Sex differences in autism spectrum disorder: a review

SL Ferri, T Abel, ES Brodkin - Current psychiatry reports, 2018 - Springer
Abstract Purpose of Review Neurodevelopmental disorders disproportionately affect males.
The mechanisms underlying male vulnerability or female protection are not known and …

A genetically encoded sensor measures temporal oxytocin release from different neuronal compartments

T Qian, H Wang, P Wang, L Geng, L Mei… - Nature …, 2023 - nature.com
Oxytocin (OT), a peptide hormone and neuromodulator, is involved in diverse physiological
and pathophysiological processes in the central nervous system and the periphery …

[HTML][HTML] Social touch-like tactile stimulation activates a tachykinin 1-oxytocin pathway to promote social interactions

H Yu, W Miao, E Ji, S Huang, S Jin, X Zhu, MZ Liu… - Neuron, 2022 - cell.com
It is well known that affective and pleasant touch promotes individual well-being and
facilitates affiliative social communication, although the neural circuit that mediates this …

An allostatic theory of oxytocin

DS Quintana, AJ Guastella - Trends in cognitive sciences, 2020 - cell.com
Oxytocin has garnered considerable interest for its role in social behavior, as well as for the
potential of intranasal administration to treat social difficulties. However, current theoretical …

The effect of oxytocin nasal spray on social interaction deficits observed in young children with autism: a randomized clinical crossover trial

CJ Yatawara, SL Einfeld, IB Hickie, TA Davenport… - Molecular …, 2016 - nature.com
Interventions for autism are limited. The synthetic hormone oxytocin may provide a potential
treatment to improve core social and behavioral difficulties in autism, but its efficacy has yet …

Autism spectrum disorder in adults: diagnosis, management, and health services development

CM Murphy, CE Wilson, DM Robertson… - Neuropsychiatric …, 2016 - Taylor & Francis
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized
by pervasive difficulties since early childhood across reciprocal social communication and …

Intranasal oxytocin in the treatment of autism spectrum disorders: A multilevel meta-analysis

Y Huang, X Huang, RP Ebstein, R Yu - Neuroscience & Biobehavioral …, 2021 - Elsevier
Intranasal oxytocin has been shown to promote social functioning and has recently been
applied as a treatment for autism spectrum disorders (ASD). The current meta-analysis aims …

The correlation between central and peripheral oxytocin concentrations: a systematic review and meta-analysis

M Valstad, GA Alvares, M Egknud… - Neuroscience & …, 2017 - Elsevier
There is growing interest in the role of the oxytocin system in social cognition and behavior.
Peripheral oxytocin concentrations are regularly used to approximate central concentrations …

A cortical circuit for sexually dimorphic oxytocin-dependent anxiety behaviors

K Li, M Nakajima, I Ibañez-Tallon, N Heintz - Cell, 2016 - cell.com
The frequency of human social and emotional disorders varies significantly between males
and females. We have recently reported that oxytocin receptor interneurons (OxtrINs) …