Ecology of aspergillosis: insights into the pathogenic potency of Aspergillus fumigatus and some other Aspergillus species

C Paulussen, JE Hallsworth… - Microbial …, 2017 - Wiley Online Library
Fungi of the genus Aspergillus are widespread in the environment. Some Aspergillus
species, most commonly Aspergillus fumigatus, may lead to a variety of allergic reactions …

DNA barcoding of fungi causing infections in humans and animals

L Irinyi, M Lackner, GS De Hoog, W Meyer - Fungal biology, 2016 - Elsevier
Correct species identification is becoming increasingly important in clinical diagnostics. Till
now, many mycological laboratories rely on conventional phenotypic identification. But this …

Mitogen activated protein kinases SakAHOG1 and MpkC collaborate for Aspergillus fumigatus virulence

ACMO Bruder Nascimento, TF Dos Reis… - Molecular …, 2016 - Wiley Online Library
Here, we investigated which stress responses were influenced by the MpkC and SakA
mitogen‐activated protein kinases of the high‐osmolarity glycerol (HOG) pathway in the …

The Aspergillus fumigatus CrzA Transcription Factor Activates Chitin Synthase Gene Expression during the Caspofungin Paradoxical Effect

LNA Ries, MC Rocha, PA De Castro, R Silva-Rocha… - MBio, 2017 - Am Soc Microbiol
Aspergillus fumigatus is an opportunistic fungal pathogen that causes invasive aspergillosis
(IA), a life-threatening disease in immunocompromised humans. The echinocandin …

Genome‐wide transcriptome analysis of Aspergillus fumigatus exposed to osmotic stress reveals regulators of osmotic and cell wall stresses that are SakAHOG1 and …

L Pereira Silva, P Alves de Castro… - Cellular …, 2017 - Wiley Online Library
Invasive aspergillosis is predominantly caused by Aspergillus fumigatus, and adaptations to
stresses experienced within the human host are a prerequisite for the survival and virulence …

The current status of avian aspergillosis diagnoses: veterinary practice to novel research avenues

MG Savelieff, L Pappalardo… - Veterinary clinical …, 2018 - Wiley Online Library
Aspergillus fungal infections continue to be a significant cause of morbidity and mortality in
birds that can, in part, be attributed to the lack of a diagnostic “gold standard” for Aspergillus …

Current challenges in the diagnosis of fungal infections

C Lass-Flörl - Human fungal pathogen identification: methods and …, 2017 - Springer
Diagnosing fungal infections is a challenge, particularly in the immunocompromised host.
Signs and symptoms are nonspecific, colonization is difficult to distinguish from invasive …

Aspergillus fumigatus High Osmolarity Glycerol Mitogen Activated Protein Kinases SakA and MpkC Physically Interact During Osmotic and Cell Wall Stresses

AO Manfiolli, EC Mattos, LJ De Assis, LP Silva… - Frontiers in …, 2019 - frontiersin.org
Aspergillus fumigatus, a saprophytic filamentous fungus, is a serious opportunistic pathogen
of mammals and it is the primary causal agent of invasive aspergillosis (IA). Mitogen …

The Aspergillus fumigatus phosphoproteome reveals roles of high-osmolarity glycerol mitogen-activated protein kinases in promoting cell wall damage and …

EC Mattos, LP Silva, C Valero, PA de Castro… - MBio, 2020 - Am Soc Microbiol
The filamentous fungus Aspergillus fumigatus can cause a distinct set of clinical disorders in
humans. Invasive aspergillosis (IA) is the most common life-threatening fungal disease of …

Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance

PA de Castro, AC Colabardini, AO Manfiolli… - PLoS …, 2019 - journals.plos.org
Aspergillus fumigatus causes invasive aspergillosis, the most common life-threatening
fungal disease of immuno-compromised humans. The treatment of disseminated infections …