Abstract The 2021 WHO Classification of Thoracic Tumours was published earlier this year,
with classification of lung tumors being one of the chapters. The principles remain those of …

All solid tumours require a vascular supply in order to progress. Although the ability to
induce angiogenesis (new blood vessel growth) has long been regarded as essential to this …

Introduction A grading system for pulmonary adenocarcinoma has not been established.
The International Association for the Study of Lung Cancer pathology panel evaluated a set …

Lung adenocarcinomas (LUADs) display a broad histological spectrum from low-grade
lepidic tumors through to mid-grade acinar and papillary and high-grade solid, cribriform …

Objective: Accurate diagnosis and prognosis are essential in lung cancer treatment
selection and planning. With the rapid advance of medical imaging technology, whole slide …

This article proposes codes for the primary tumor categories of adenocarcinoma in situ (AIS)
and minimally invasive adenocarcinoma (MIA) and a uniform way to measure tumor size in …

Metastasis is initiated and sustained through therapy by cancer cells with stem-like and
immune-evasive properties, termed metastasis-initiating cells (MIC). Recent progress …

Abstract The 2015 World Health Organization (WHO) Classification of Tumors of the Lung,
Pleura, Thymus and Heart has just been published with numerous important changes from …

Lung cancer continues to be a major global health problem; the disease is diagnosed in
more than 1.6 million new patients each year. However, significant progress is underway in …

Introduction Spread through air spaces (STAS) is a form of invasion wherein tumor cells
extend beyond the tumor edge within the lung parenchyma. In lung adenocarcinoma (ADC) …