Current status of clinical trials assessing mesenchymal stem cell therapy for graft versus host disease: a systematic review

Y Li, J Hao, Z Hu, YG Yang, Q Zhou, L Sun… - Stem Cell Research & …, 2022 - Springer
Background Graft-versus-host disease (GVHD) is a common fatal complication of
hematopoietic stem cell transplantation (HSCT), where steroids are used as a treatment …

[HTML][HTML] Cell-based therapy in prophylaxis and treatment of chronic graft-versus-host disease

M Doglio, RE Crossland, AC Alho, O Penack… - Frontiers in …, 2022 - frontiersin.org
Hematopoietic allogeneic stem cell transplantation (allo-SCT) is a curative option for
patients with hematological malignancies. However, due to disparities in major and minor …

Axatilimab for chronic graft-versus-host disease after failure of at least two prior systemic therapies: results of a phase I/II study

CL Kitko, M Arora, Z DeFilipp, MA Zaid… - Journal of Clinical …, 2023 - ingentaconnect.com
PURPOSE Chronic graft-versus-host disease (cGVHD) remains the major cause of late
morbidity after allogeneic hematopoietic cell transplantation. Colony-stimulating factor 1 …

[HTML][HTML] Management of chronic graft-vs.-host disease in children and adolescents with ALL: present status and model for a personalised management plan

A Sobkowiak-Sobierajska, C Lindemans… - Frontiers in …, 2022 - frontiersin.org
Herein we review current practice regarding the management of chronic graft-vs.-host
disease (cGvHD) in paediatric patients after allogeneic haematopoietic stem cell …

Improved therapeutic approaches are needed to manage graft-versus-host disease

DS Hooker, K Grabe-Heyne, C Henne, P Bader… - Clinical drug …, 2021 - Springer
Allogeneic haematopoietic stem cell transplantation (alloHSCT) offers a potentially curative
therapy for patients suffering from diseases of the haematopoietic system but requires a high …

Ruxolitinib in patients with graft versus host disease (GvHD): findings from a compassionate use program

T Pattipaka, S Sarp, P Nakhaei, S Güneş - Bone Marrow …, 2024 - nature.com
The ruxolitinib compassionate use (CU) program offered ruxolitinib to patients≥ 2 years of
age with confirmed steroid-resistant acute or chronic graft-versus-host disease (aGvHD and …

Established and emerging treatments of skin GvHD

CS Link-Rachner, K Sockel, C Schuetz - Frontiers in Immunology, 2022 - frontiersin.org
Graft-versus-host disease (GvHD) of the skin is a severe allo-immune reaction and
complication following allogeneic stem cell transplantation. Over the past years, intensive …

Second line extracorporeal photopheresis for cortico-resistant acute and chronic GVHD after allogeneic hematopoietic cell transplantation for hematological …

M Michallet, M Sobh, A Deloire, D Revesz… - … and Apheresis Science, 2024 - Elsevier
Abstract Background & Objectives The primary objective of this observational study was to
perform an exhaustive description concerning patients receiving extracorporeal …

Infectious risks in patients treated with extracorporeal photopheresis for graft‐versus‐host disease: A retrospective cohort study

U Thevenet, E Daguenet, SM Beszera… - Journal of Clinical …, 2022 - Wiley Online Library
Background Infections are common with significant mortality and morbidity in patients with
graft‐versus‐host disease (GvHD). Extracorporeal photopheresis (ECP) is an advantageous …

Impact of extracorporeal photopheresis on blood and coagulation parameters

T Gambichler, M Chatzipantazi… - Dermatologic …, 2022 - Wiley Online Library
Extracorporeal photopheresis (ECP) is considered a safe treatment modality. We aimed to
assess blood parameters including coagulation during ECP over time. We performed a long …