The keratins are the typical intermediate filament proteins of epithelia, showing an
outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing …

Keratins are a diverse group of structural proteins that form the intermediate filament network
responsible for maintaining the structural integrity of keratinocytes. In humans, there are …

Proteomic analysis of samples isolated by laser capture microdissection from clinical
specimens requires sample preparation and fractionation methods suitable for small …

Extrapulmonary small cell carcinomas (EPSCCs) are uncommon malignant neoplasms with
a reported incidence of 0.1% to 0.4% in the United States. Since their first description in …

The role of fine needle aspiration biopsy (FNAB) in the evaluation of focal liver lesions has
evolved. Guided FNAB is still useful to procure a tissue diagnosis if clinical, biochemical and …

Hepatocellular carcinoma (HCC) is known for its histomorphologic heterogeneity.
Immunohistochemistry (IHC) can help in the comparative morphologic evaluation of HCC, its …

Clinical, histopathologic, immunohistochemical, and genetic analyses of 2 osteoclastic giant
cell tumors of the pancreas are presented. The neoplasms were composed of osteoclastic …

Metastatic adenocarcinoma to the liver from an unidentified primary tumor site is a common
diagnostic problem. The present study included 41 cases of histologically diagnosed liver …

Everyone who has taken the course in radiologic pathology at the Armed Forces Institute of
Pathology (AFIP) remembers bringing beautifully illustrated cases for accession to the …

A 2-year-old male Thoroughbred was evaluated for multiple firm, raised nodules of the
maxilla and mandible that had been present since 6 months of age. The horse was …