Pharmacokinetics and pharmacodynamics of direct oral anticoagulants

B Hindley, GYH Lip, AP McCloskey… - Expert Opinion on Drug …, 2023 - Taylor & Francis
ABSTRACT Introduction Direct oral anticoagulants (DOACs) have overtaken vitamin K
antagonists to become the most widely used method of anticoagulation for most indications …

[HTML][HTML] Platelet-rich fibrin ensures hemostasis after single-tooth removal under factor Xa inhibitors—a clinical prospective randomized split-mouth study

S Kyyak, A Jari, D Heimes, J Heider… - Clinical oral …, 2023 - Springer
Objectives In this prospective, double-blinded, randomized split-mouth study, the local
hemostatic effect of platelet-rich fibrin (PRF) inserted into the extraction socket in patients …

[HTML][HTML] Practices, beliefs, and attitudes of clinicians in prescribing direct oral anticoagulants for obese adults with atrial fibrillation: a qualitative study

F Shaikh, R Wynne, RL Castelino, SC Inglis… - International Journal of …, 2023 - Springer
Background Atrial fibrillation (AF) and obesity affect over 60 and 650 million people,
respectively. Aim This study aimed to explore clinician practices, beliefs, and attitudes …

[HTML][HTML] Direct oral anticoagulants and the risk of adverse clinical outcomes among patients with different body weight categories: a large hospital-based study

EM Nwanosike, HA Merchant, W Sunter… - European Journal of …, 2024 - Springer
Objective Through predictable pharmacokinetics—including a convenient fixed-dose
regimen, direct oral anticoagulants (DOACs) are preferred over previous treatments in …

A Real-World Exploration into Clinical Outcomes of Direct Oral Anticoagulant Dosing Regimens in Morbidly Obese Patients Using Data-Driven Approaches

EM Nwanosike, W Sunter, MA Ansari… - American Journal of …, 2023 - Springer
Introduction The clinical outcomes of direct oral anticoagulant (DOAC) dosage regimens in
morbid obesity are uncertain due to limited clinical evidence. This study seeks to bridge this …

Impact of body mass index on venous thromboembolism recurrence with direct oral anticoagulants

SJ Gaddam, US Grewal, TS Brown… - The American …, 2023 - pubmed.ncbi.nlm.nih.gov
Impact of body mass index on venous thromboembolism recurrence with direct oral
anticoagulants Impact of body mass index on venous thromboembolism recurrence with direct …

Efficacy, safety, and feasibility of Apixaban for postoperative venous thromboembolism prophylaxis following open gynecologic cancer surgery at a comprehensive …

A Knisely, MD Iniesta, S Batman, LA Meyer… - Gynecologic …, 2024 - Elsevier
Objectives To evaluate safety, efficacy, and feasibility of apixaban for postoperative venous
thromboembolism (VTE) prophylaxis following open gynecologic cancer surgery at a …

[HTML][HTML] Современные возможности использования лабораторных методов контроля эффективности и безопасности применения прямых пероральных …

СР Гиляревский, НК Вереина… - Рациональная …, 2023 - cyberleninka.ru
Рассмотрены современные подходы к использованию лабораторных методов для
усовершенствования тактики применения прямых пероральных антикоагулянтов …

Clinical considerations for rational use of oral anticoagulant therapy

Y Van Heerden - SA Pharmaceutical Journal, 2023 - journals.co.za
Patients who are at risk for venous thromboembolism may require prophylaxis with oral
anticoagulant agents. In South Africa, available oral anticoagulant agents include warfarin …

[HTML][HTML] Current insights into the possible role of laboratory monitoring of effectiveness and safety of direct oral anticoagulants

SR Gilyarevsky, NK Vereina… - Rational …, 2023 - rpcardio.elpub.ru
The article is devoted to the discussion of modern approaches to the use of laboratory
methods to improve the tactics of using direct oral anticoagulants (DOACs) therapy. Clinical …