Can we selectively reduce appetite for energy-dense foods? An overview of pharmacological strategies for modification of food preference behavior

E Bojanowska, J Ciosek - Current Neuropharmacology, 2016 - ingentaconnect.com
Excessive intake of food, especially palatable and energy-dense carbohydrates and fats, is
largely responsible for the growing incidence of obesity worldwide. Although there are a …

5-HT2C Receptor Stimulation in Obesity Treatment: Orthosteric Agonists vs. Allosteric Modulators

E Przegaliński, K Witek, K Wydra, JH Kotlińska, M Filip - Nutrients, 2023 - mdpi.com
Obesity is a substantial health and economic issue, and serotonin (5-hydroxytryptamine, 5-
HT) is an important neurotransmitter system involved in the regulation of body weight. The 5 …

Idalopirdine – a small molecule antagonist of 5-HT6 with therapeutic potential against obesity

M Dudek, M Marcinkowska, A Bucki, A Olczyk… - Metabolic Brain …, 2015 - Springer
Abstract 5HT 6 receptor antagonists offer the potential for safe and effective drugs against
obesity, because they can reduce weight without causing serious side effects in the …

Сибутрамин: эффективность и безопасность применения в рутинной клинической практике

ТИ Романцова - Ожирение и метаболизм, 2015 - cyberleninka.ru
В мае 2015 г. в Дублине состоялся 17-й Европейский конгресс по эндокринологии. В
рамках секции≪ Ожирение≫ были представлены предварительные результаты …

Selective serotonin receptor stimulation of the medial nucleus accumbens differentially affects appetitive motivation for food on a progressive ratio schedule of …

WE Pratt, MA Schall, E Choi - Neuroscience letters, 2012 - Elsevier
Previously, we reported that stimulation of selective serotonin (5-HT) receptor subtypes in
the nucleus accumbens shell differentially affected consumption of freely available food …

Sibutramine: efficacy and safety of prescribing in routine clinical practice

TI Romantsova - Obesity and metabolism, 2015 - omet-endojournals.ru
Abstract The 17th European Congress of endocrinology was held in Dublin in May 2015.
Within the section «Obesity» the preliminary results of the observational program" …

Olanzapine and sibutramine have opposing effects on the motivation for palatable food

EM van der Zwaal, SK Janhunen… - Behavioural …, 2012 - journals.lww.com
Both olanzapine and sibutramine target serotonergic and noradrenergic neurotransmission
and influence body weight, but in opposite ways. The second-generation antipsychotic …

Inverse agonism at α2A adrenoceptors augments the hypophagic effect of sibutramine in rats

SK Janhunen, EM Van Der Zwaal, SE La Fleur… - …, 2011 - Wiley Online Library
Because the use of monoamine reuptake inhibitors as weight‐reducing agents is limited by
adverse effects, novel antiobesity drugs are needed. We studied acute effects of the …

[PDF][PDF] Comparison of the effects of cuminum cyminuml and sibutramine on weight, serum leptin, glucose and lipids in rat

AJ MOHITI, Z Akbarian, AMR PIRI, AA MOHITI - 2012 - sid.ir
Objectives: Diabetes is one of the most common metabolic diseases in the world. It affects
6.6% of world population and about 3 million individuals in Iran. Nowadays chemical and …

Animal models to explore the effects of CNS drugs on food intake and energy expenditure

SP Vickers, PG Clifton - Neuropharmacology, 2012 - Elsevier
Obesity has reached epidemic proportions globally with an increasing incidence not just in
Western cultures but also Mexico, Brazil, China and parts of Africa. In terms of …