Cardiac autonomic neuropathy (CAN) is a serious complication of diabetes mellitus (DM)
that is strongly associated with approximately five-fold increased risk of cardiovascular …

The association of chronic glycemia, measured by HbA1c, with long-term complications of
type 1 diabetes has been well established in the Diabetes Control and Complications Trial …

Diabetes mellitus (type 1 and type 2) and the complications associated with this condition
are an urgent public health problem, as the incidence of diabetes mellitus is steadily …

OBJECTIVE The Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D)
trial demonstrated similar long-term clinical effectiveness of insulin-sensitizing (IS) versus …

Aims/hypothesis The study aimed to assess the impact on neuropathy of simultaneous
pancreas and kidney transplantation (SPK) in individuals with type 1 diabetes. Methods This …

There is a high prevalence of painful diabetic polyneuropathy (pDPN) with around one-third
of all patients with diabetes suffering from pDPN. pDPN has debilitating consequences, with …

Abstract Purpose of Review Painful diabetic neuropathy (PDN) manifests with pain typically
in the distal lower extremities and can be challenging to treat. The authors appraised the …

Summary T1DM neuropathy and T2DM neuropathy are fundamentally different. In T1DM,
glucose control has a large effect on the prevention of neuropathy; therefore, future efforts …

Diabetic neuropathy is the most common and debilitating complication of diabetes mellitus
with more than half of all patients developing altered sensation as a result of damage to …

Incredible strides have been made since the discovery of insulin almost 100 years ago.
Insulin formulations have improved dramatically, glucose levels can be measured …