OBJECTIVE The Diabetes Control and Complications Trial/Epidemiology of Diabetes
Interventions and Complications (DCCT/EDIC) study continues to address knowledge gaps …

Diabetes is the leading cause of neuropathy in North America (1). Estimates of the
prevalence vary depending on the diagnostic criteria and population studied. A reasonable …

OBJECTIVE To estimate the prevalence of and risk factors for diabetic peripheral
neuropathy (DPN) in a pilot study among youth participating in the SEARCH for Diabetes in …

Diabetes mellitus (DM) has 4 major complications: neuropathy, retinopathy, nephropathy,
and vasculopathy. The various neuropathies associated with DM can clinically be divided …

The prevalence of diabetic polyneuropathy (DPN) can approach 50% in subjects with longer-
duration diabetes. The most common neuropathies are generalized symmetrical chronic …

Abstract The DCCT/EDIC (Diabetes Control and Complications Trial/Epidemiology of
Diabetes Interventions and Complications) provides a comprehensive characterization of …

Introduction This review highlights the pathogenesis of both microvascular and
macrovascular complications of diabetes and how these mechanisms influence both the …

Diabetic distal symmetric polyneuropathy (DSPN) occurs in around one‐third of patients with
diabetes and is associated with significant morbidity and increased mortality. Diagnosis and …

Diabetes mellitus is a potent upstream event in the molecular pathophysiology which gives
rise to various diabetes-related complications. There are several classes of anti-diabetic …

Abstract Purpose of Review: Diabetes is the most common cause of peripheral neuropathy
in the world. More than half of patients with diabetes have neuropathy, and half of patients …