[HTML][HTML] Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment

M Zhang, W Hu, C Cai, Y Wu, J Li, S Dong - Materials Today Bio, 2022 - Elsevier
Inflammatory arthritis is a major cause of disability in the elderly. This condition causes joint
pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and …

Hyaluronic acid: A key ingredient in the therapy of inflammation

A Marinho, C Nunes, S Reis - Biomolecules, 2021 - mdpi.com
Hyaluronic acid (HA) is a natural polymer, produced endogenously by the human body,
which has unique physicochemical and biological properties, exhibiting desirable …

Proton-driven transformable nanovaccine for cancer immunotherapy

N Gong, Y Zhang, X Teng, Y Wang, S Huo… - Nature …, 2020 - nature.com
Cancer vaccines hold great promise for improved cancer treatment. However, endosomal
trapping and low immunogenicity of tumour antigens usually limit the efficiency of …

Rheumatoid arthritis microenvironment insights into treatment effect of nanomaterials

Y Zhu, T Zhao, M Liu, S Wang, S Liu, Y Yang, Y Yang… - Nano Today, 2022 - Elsevier
Rheumatoid arthritis (RA) causes a huge medical burden due to its high morbidity and
disability rate. Emerging evidences demonstrate that RA has a tumor-like microenvironment …

Nanoparticles in nanomedicine: a comprehensive updated review on current status, challenges and emerging opportunities

HM Abdel-Mageed, NZ AbuelEzz… - Journal of …, 2021 - Taylor & Francis
The fast progress in nanomedicine and nanoparticles (NP) materials presents
unconventional solutions which are expected to revolutionise health care with great …

Multi-bioresponsive silk fibroin-based nanoparticles with on-demand cytoplasmic drug release capacity for CD44-targeted alleviation of ulcerative colitis

S Gou, Y Huang, Y Wan, Y Ma, X Zhou, X Tong… - Biomaterials, 2019 - Elsevier
The requirement for the favorable therapeutics against ulcerative colitis (UC) is that anti-
inflammatory drugs can be specifically internalized by macrophages and subsequently be …

Bioresponsive drug delivery systems for the treatment of inflammatory diseases

Y Dou, C Li, L Li, J Guo, J Zhang - Journal of controlled release, 2020 - Elsevier
Inflammation is intimately related to the pathogenesis of numerous acute and chronic
diseases like cardiovascular disease, inflammatory bowel disease, rheumatoid arthritis, and …

Intra-articular targeting of nanomaterials for the treatment of osteoarthritis

S Brown, S Kumar, B Sharma - Acta biomaterialia, 2019 - Elsevier
Osteoarthritis is a prevalent and debilitating disease that involves pathological contributions
from numerous joint tissues and cells. The joint is a challenging arena for drug delivery …

Towards an arthritis flare-responsive drug delivery system

N Joshi, J Yan, S Levy, S Bhagchandani… - Nature …, 2018 - nature.com
Local delivery of therapeutics for the treatment of inflammatory arthritis (IA) is limited by short
intra-articular half-lives. Since IA severity often fluctuates over time, a local drug delivery …

Application of hyaluronic acid in tissue engineering, regenerative medicine, and nanomedicine: A review

K Saravanakumar, SJ Park, SS Santosh… - International Journal of …, 2022 - Elsevier
Hyaluronic acid (HA) plays a vital role in cellular processes and its contribution to physical
and immunological barriers is considered to be an important property for the formulation of …