[HTML][HTML] Nanomedicines for the treatment of rheumatoid arthritis: State of art and potential therapeutic strategies

Q Wang, X Qin, J Fang, X Sun - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Increasing understanding of the pathogenesis of rheumatoid arthritis (RA) has remarkably
promoted the development of effective therapeutic regimens of RA. Nevertheless, the …

Microenvironment-responsive nanocarriers for targeted bone disease therapy

M Li, B Yu, S Wang, F Zhou, J Cui, J Su - Nano Today, 2023 - Elsevier
Nanomedicines with controlled drug release have received increasing attention as an
advanced therapeutic strategy for bone diseases. To traverse biological barriers towards …

Hyaluronic acid–based activatable nanomaterials for stimuli‐responsive imaging and therapeutics: beyond CD44‐mediated drug delivery

KY Choi, HS Han, ES Lee, JM Shin… - Advanced …, 2019 - Wiley Online Library
There is a rapidly increasing interest in developing stimuli‐responsive nanomaterials for
treating a variety of diseases. By enabling the activation of function locally at the sites of …

[HTML][HTML] Novel drug delivery systems for NSAIDs in management of rheumatoid arthritis: An overview

S Thakur, B Riyaz, A Patil, A Kaur, B Kapoor… - Biomedicine & …, 2018 - Elsevier
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic joint
inflammation which ultimately leads to severe disability and premature mortality. It has a …

Knee osteoarthritis therapy: recent advances in intra-articular drug delivery systems

L Ma, X Zheng, R Lin, ARJ Sun, J Song… - Drug design …, 2023 - Taylor & Francis
Drug delivery for osteoarthritis (OA) treatment is a continuous challenge because of their
poor bioavailability and rapid clearance in joints. Intra-articular (IA) drug delivery is a …

Palmitic acid-modified bovine serum albumin nanoparticles target scavenger receptor-A on activated macrophages to treat rheumatoid arthritis

T Gong, T Tan, P Zhang, H Li, C Deng, Y Huang… - Biomaterials, 2020 - Elsevier
Palmitic acid-modified bovine serum albumin (PAB) was synthetized and found to own
remarkable scavenger receptor-A (SR-A) targeting ability in vitro and in vivo, through which …

Rational design of metal-organic frameworks to deliver methotrexate for targeted rheumatoid arthritis therapy

L Guo, Y Chen, T Wang, Y Yuan, Y Yang, X Luo… - Journal of Controlled …, 2021 - Elsevier
Methotrexate (MTX) has been used as an anchor drug for the treatment of rheumatoid
arthritis (RA), while the patients with chronic MTX administration suffer from severe side …

Hierarchical superparamagnetic metal–organic framework nanovectors as anti-inflammatory nanomedicines

H Zhao, S Sene, AM Mielcarek, S Miraux… - Journal of Materials …, 2023 - pubs.rsc.org
Among a plethora of drug nanocarriers, biocompatible nanoscale metal–organic frameworks
(nanoMOFs) with a large surface area and an amphiphilic internal microenvironment have …

A comprehensive review of advanced drug delivery systems for the treatment of rheumatoid arthritis

Q Shen, Y Du - International Journal of Pharmaceutics, 2023 - Elsevier
Rheumatoid arthritis (RA), a chronic autoimmune disease, is characterized by articular pain
and swelling, synovial hyperplasia, and cartilage and bone destruction. Conventional …

A multifunctional nanoaggregate‐based system for detection of rheumatoid arthritis via optoacoustic/NIR‐II fluorescent imaging and therapy via inhibiting JAK‐STAT …

J Chen, L Chen, Z She, F Zeng, S Wu - Aggregate, 2024 - Wiley Online Library
Rheumatoid arthritis (RA) is a debilitating autoimmune disease that causes chronic pain and
serious complications, presenting a significant challenge to treat. Promising approaches for …