Inflammatory microenvironments (IMEs) are common pathological characteristics and drive
the development of multiple chronic diseases. Thus, IME-targeted therapies exhibit potential …

Introduction Rheumatoid arthritis (RA) is an autoimmune systemic disease in which
inflammatory and immune cells accumulate in inflamed joints. Researchers aimed at the …

Osteoarthritis (OA) is a common and complex inflammatory disorder that is frequently
compounded by cartilage degradation, synovial inflammation, and osteophyte formation …

Rheumatoid arthritis (RA), a common inflammatory disorder of the joints characterized by
synovitis and pannus formation, often results in irreversible joint erosion and disability …

Owing to its intricate autoimmune pathophysiology and significant risks of progression to
other rheumatic co-morbidities (ie, osteoporosis and osteoarthritis), a plausible therapeutic …

Rheumatoid arthritis (RA) is a chronic and symmetrical autoimmune disease that primarily
characterized with articular synovial hyperplasia, joint swelling, cartilage and bone …

Rheumatoid arthritis (RA) is an immune-mediated inflammatory disease that selectively
attacks human joints. The common non-targeted treatment approaches lead to obvious side …

Over the past few decades, enhanced permeability of tumor vasculature was actively
exploited for targeted delivery of anticancer nanomedicines resulting in numerous …

Rheumatoid arthritis (RA) patients have suffered from the current drug therapeutic regimen
because of its high toxicity and the absence of bone regeneration for existing erosion …

Hyaluronic acid (HA), a biodegradable, biocompatible and non-immunogenic therapeutic
polymer is a key component of the cartilage extracellular matrix (ECM) and has been widely …