Macrophage polarization and diabetic wound healing

AE Louiselle, SM Niemiec, C Zgheib, KW Liechty - Translational research, 2021 - Elsevier
Diabetes mellitus is a costly disease and nearly one-third of these costs are attributed to
management of diabetic foot disease including chronic, non-healing, diabetic foot ulcers …

Roles of human serum albumin in prediction, diagnoses and treatment of COVID-19

G Rabbani, SN Ahn - International Journal of Biological Macromolecules, 2021 - Elsevier
The severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) keeps on destroying
normal social integrity worldwide, bringing about extraordinary medical services, cultural …

[HTML][HTML] Lactylation of PKM2 suppresses inflammatory metabolic adaptation in pro-inflammatory macrophages

J Wang, P Yang, T Yu, M Gao, D Liu… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Emerging evidence suggests that metabolic adaptation is a vital hallmark and prerequisite
for macrophage phenotype transition. Pyruvate kinase M2 (PKM2) is an essential molecular …

Responsive hydrogel-based microneedle dressing for diabetic wound healing

Z Guo, H Liu, Z Shi, L Lin, Y Li, M Wang… - Journal of Materials …, 2022 - pubs.rsc.org
Wound healing is a critical challenge in diabetic patients, mainly due to long-term
dysglycemia and its related pathological complications. Subcutaneous insulin injection …

[HTML][HTML] Modulation of macrophages by a paeoniflorin-loaded hyaluronic acid-based hydrogel promotes diabetic wound healing

H Yang, L Song, B Sun, D Chu, L Yang, M Li, H Li… - Materials Today Bio, 2021 - Elsevier
The impaired wound healing in diabetes is a central concern of healthcare worldwide.
However, current treatments often fail due to the complexity of diabetic wounds, and thus …

A frog peptide provides new strategies for the intervention against skin wound healing

C Li, Z Fu, T Jin, Y Liu, N Liu, S Yin, Z Wang… - Cellular & Molecular …, 2023 - Springer
Background Amphibian derived pro-healing peptides as molecular probes might provide a
promising strategy for development of drug candidates and elucidation of cellular and …

New horizons of macrophage immunomodulation in the healing of diabetic foot ulcers

CW Lin, CM Hung, WJ Chen, JC Chen, WY Huang… - Pharmaceutics, 2022 - mdpi.com
Diabetic foot ulcers (DFUs) are one of the most costly and troublesome complications of
diabetes mellitus. The wound chronicity of DFUs remains the main challenge in the current …

Macrophage polarization in diabetic wound healing

X Wu, W He, X Mu, Y Liu, J Deng, Y Liu, X Nie - Burns & Trauma, 2022 - academic.oup.com
Impaired wound healing is one of the severe complications of diabetes. Macrophages have
been shown to play a vital role in wound healing. In different wound environments …

Liver macrophages and inflammation in physiology and physiopathology of non‐alcoholic fatty liver disease

R Thibaut, MC Gage, I Pineda‐Torra… - The FEBS …, 2022 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome, being a common comorbidity of type 2 diabetes and with important links to …

Targeting insulin-degrading enzyme in insulin clearance

MA Leissring, CM González-Casimiro… - International journal of …, 2021 - mdpi.com
Hepatic insulin clearance, a physiological process that in response to nutritional cues
clears~ 50–80% of circulating insulin, is emerging as an important factor in our …