Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications
Significance: Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique to
distinguish the unique molecular environment of fluorophores. FLIM measures the time a …
distinguish the unique molecular environment of fluorophores. FLIM measures the time a …
Phosphorescent iridium (III) complexes as lifetime-based biological sensors for photoluminescence lifetime imaging microscopy
J Zhou, J Li, KY Zhang, S Liu, Q Zhao - Coordination Chemistry Reviews, 2022 - Elsevier
Luminescent iridium (III) complexes exhibit high phosphorescence quantum yields and
photostability, good cell membrane permeability, rich and sensitive photophysical …
photostability, good cell membrane permeability, rich and sensitive photophysical …
Label-free sensing of cells with fluorescence lifetime imaging: the quest for metabolic heterogeneity
EA Shirshin, MV Shirmanova… - Proceedings of the …, 2022 - National Acad Sciences
Molecular, morphological, and physiological heterogeneity is the inherent property of cells
which governs differences in their response to external influence. Tumor cell metabolic …
which governs differences in their response to external influence. Tumor cell metabolic …
Recent progress in functionalized and targeted polymersomes and chimeric polymeric nanotheranostic platforms for cancer therapy
M Beygi, F Oroojalian, SS Hosseini… - Progress in Materials …, 2023 - Elsevier
The majority of advances in cancer therapy have been achieved based on developments in
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …
[HTML][HTML] Compressed sensing in fluorescence microscopy
Compressed sensing (CS) is a signal processing approach that solves ill-posed inverse
problems, from under-sampled data with respect to the Nyquist criterium. CS exploits …
problems, from under-sampled data with respect to the Nyquist criterium. CS exploits …
FLIM as a promising tool for cancer diagnosis and treatment monitoring
Fluorescence lifetime imaging microscopy (FLIM) has been rapidly developed over the past
30 years and widely applied in biomedical engineering. Recent progress in fluorophore …
30 years and widely applied in biomedical engineering. Recent progress in fluorophore …
Current advances in lipid nanosystems intended for topical and transdermal drug delivery applications
N Akombaetwa, AB Ilangala, L Thom, PB Memvanga… - Pharmaceutics, 2023 - mdpi.com
Skin delivery is an exciting and challenging field. It is a promising approach for effective drug
delivery due to its ease of administration, ease of handling, high flexibility, controlled …
delivery due to its ease of administration, ease of handling, high flexibility, controlled …
Molecularly Engineered Room-Temperature Phosphorescence for Biomedical Application: From the Visible toward Second Near-Infrared Window
Phosphorescence, characterized by luminescent lifetimes significantly longer than that of
biological autofluorescence under ambient environment, is of great value for biomedical …
biological autofluorescence under ambient environment, is of great value for biomedical …
Short‐wave Infrared Photoluminescence Lifetime Mapping of Rare‐Earth Doped Nanoparticles Using All‐Optical Streak Imaging
The short‐wave infrared (SWIR) photoluminescence lifetimes of rare‐earth doped
nanoparticles (RENPs) have found diverse applications in fundamental and applied …
nanoparticles (RENPs) have found diverse applications in fundamental and applied …
Fluorescence lifetime imaging with a megapixel SPAD camera and neural network lifetime estimation
Fluorescence lifetime imaging microscopy (FLIM) is a key technology that provides direct
insight into cell metabolism, cell dynamics and protein activity. However, determining the …
insight into cell metabolism, cell dynamics and protein activity. However, determining the …