Synergistically dual-functional nano eye-drops for simultaneous anti-inflammatory and anti-oxidative treatment of dry eye disease

YJ Li, LJ Luo, SG Harroun, SC Wei, B Unnikrishnan… - Nanoscale, 2019 - pubs.rsc.org
We have developed a rapid and straightforward topical treatment method for dry eye
disease (DED) using poly (catechin) capped-gold nanoparticles (Au@ Poly-CH NPs) …

New potent antibacterial oxazolidinone (MRX-I) with an improved class safety profile

MF Gordeev, ZY Yuan - Journal of medicinal chemistry, 2014 - ACS Publications
Oxazolidinones comprise an important class of antibacterial protein synthesis inhibitors.
Myelosuppression and monoamine oxidase inhibition (MAOI) are key independent causes …

Clinical approach to optic neuritis: pitfalls, red flags and differential diagnosis

E Voss, P Raab, C Trebst… - Therapeutic advances in …, 2011 - journals.sagepub.com
Demyelinating optic neuritis (ON) is the most common cause of optic neuropathy typically
presenting with a subacute painful visual loss. In 20% of patients with multiple sclerosis …

Ocular iontophoresis of EGP-437 (dexamethasone phosphate) in dry eye patients: results of a randomized clinical trial

MA Patane, A Cohen, S From, G Torkildsen… - Clinical …, 2011 - Taylor & Francis
Purpose: To assess safety and efficacy of EGP-437 (dexamethasone phosphate 40 mg/mL
[DP]) in dry eye patients. Methods: The study employed a prospective, single-center, double …

Pre‐and postnatal development of the eye: A species comparison

S Van Cruchten, V Vrolyk… - Birth defects …, 2017 - Wiley Online Library
In this review paper, literature data on pre‐and postnatal eye development are compared
between humans and nonclinical species that are commonly used for human safety …

[HTML][HTML] Nonionic surfactant vesicles in ocular delivery: innovative approaches and perspectives

RK Sahoo, N Biswas, A Guha, N Sahoo… - BioMed research …, 2014 - hindawi.com
With the recent advancement in the field of ocular therapy, drug delivery approaches have
been elevated to a new concept in terms of nonionic surfactant vesicles (NSVs), that is, the …

Conjunctival and corneal tolerability assessment of ocular naltrexone niosomes and their ingredients on the hen's egg chorioallantoic membrane and excised bovine …

H Abdelkader, S Ismail, A Hussein, Z Wu… - International journal of …, 2012 - Elsevier
This study aimed at combining the hen's egg test-chorioallantoic membrane (HET-CAM),
bovine corneal opacity and permeability (BCOP) test and histological examination of …

Functional visual loss

BB Bruce, NJ Newman - Neurologic clinics, 2010 - neurologic.theclinics.com
Neurologists are frequently called on to evaluate patients complaining of vision loss. Similar
to other areas of neurology, a significant proportion of these patients have nonorganic …

Evaluation of prophylactic corticosteroid eye drop use in the management of corneal abnormalities induced by the antibody–drug conjugate mirvetuximab …

UA Matulonis, MJ Birrer, DM O'Malley, KN Moore… - Clinical Cancer …, 2019 - AACR
Purpose: Reversible, low-grade ocular adverse events (AE) are associated with
administration of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeted antibody …

Natural and iatrogenic ocular manifestations of rheumatoid arthritis: a systematic review

R Dammacco, S Guerriero, G Alessio… - International …, 2022 - Springer
Purpose To provide an overview of the ocular features of rheumatoid arthritis (RA) and of the
ophthalmic adverse drug reactions (ADRs) that may be associated with the administration of …