Interaction of systemic drugs causing ocular toxicity with organic cation transporter: an artificial intelligence prediction

M Malani, MS Hiremath, S Sharma… - Journal of …, 2023 - Taylor & Francis
Chronic disease patients (cancer, arthritis, cardiovascular diseases) undergo long-term
systemic drug treatment. Membrane transporters in ocular barriers could falsely recognize …

Taxane-Induced Neuropathy and Its Ocular Effects—A Longitudinal Follow-up Study in Breast Cancer Patients

N Stache, S Bohn, K Sperlich, C George, K Winter… - Cancers, 2023 - mdpi.com
Simple Summary The study's purpose was to determine whether neurotoxic signs in breast
cancer patients receiving taxane (paclitaxel) chemotherapy correlate with retinal or corneal …

Combination nanotherapeutics for dry eye disease treatment in a rabbit model

L Huang, H Gao, Z Wang, Y Zhong… - International Journal of …, 2021 - Taylor & Francis
Purpose Anti-inflammation is essential for dry eye disease. Traditional anti-inflammation
agent corticosteroids applied in dry eye disease (DED) treatment could result in high …

Selective estrogen receptor modulators regulate stromal proliferation in human benign prostatic hyperplasia by multiple beneficial mechanisms—action of two new …

R Kumar, V Verma, A Sarswat, JP Maikhuri… - Investigational new …, 2012 - Springer
The existing drugs for benign prostatic hyperplasia (BPH) are partially effective with
undesirable side-effects; hence new agents acting by different mechanism (s) are required …

Angiographically silent cystoid macular oedema secondary to paclitaxel therapy

CD Georgakopoulos, OE Makri, P Vasilakis… - Clinical and …, 2012 - Taylor & Francis
Bilateral macular oedema is an uncommon side‐effect of paclitaxel administration in
oncological patients. We report the case of a 64‐year‐old man who presented with …

Non-GVHD ocular complications after hematopoietic cell transplantation: expert review from the Late Effects and Quality of Life Working Committee of the CIBMTR and …

Y Inamoto, I Petriček, L Burns, S Chhabra… - Bone marrow …, 2019 - nature.com
Abstract Non-graft-vs.-host disease (non-GVHD) ocular complications are generally
uncommon after hematopoietic cell transplantation (HCT), but can cause prolonged …

Psychotropic drug-induced glaucoma: a practical guide to diagnosis and management

NS Jain, CW Ruan, SR Dhanji, RJ Symes - CNS drugs, 2021 - Springer
This article provides a practical review of the diagnosis and management of angle closure
induced by psychotropic agents, including tricyclic antidepressants, antipsychotics and …

Understanding the role of aldose reductase in ocular inflammation

UCS Yadav, SK Srivastava… - Current Molecular …, 2010 - ingentaconnect.com
Aldose reductase, although identified initially as a glucose-reducing enzyme via polyol
pathway, is believed to be an important component of antioxidant defense system as well as …

[HTML][HTML] Acute-onset bilateral myopia and ciliochoroidal effusion induced by hydrochlorothiazide

YR Roh, SJ Woo, KH Park - Korean journal of ophthalmology: KJO, 2011 - ncbi.nlm.nih.gov
The authors experienced two cases of hydrochlorothiazide (HCTZ)-induced acute-onset
bilateral myopia and shallowing of the anterior chambers. Two middle-aged women taking …

The busulfan metabolite EdAG irreversibly glutathionylates glutaredoxins

M Scian, WM Atkins - Archives of biochemistry and biophysics, 2015 - Elsevier
The DNA alkylating agent busulfan is used to 'precondition'patients with leukemia,
lymphomas and other hematological disorders prior to hematopoietic stem cell transplants …