Gastrointestinal (GI) cancer is the most common cancer in the world and one of the main
causes of cancer-related death. Clinically, surgical excision and chemotherapy are the main …

Pancreatic cancer is highly lethal, of which 90% is pancreatic ductal adenocarcinoma
(PDAC), with a 5-year survival rate of less than 12%, lacking effective treatment options and …

Chemotherapy is the commonly used treatment for advanced lung cancer. However, it
produces side effects such as the development of chemoresistance. A possible responsible …

Simple Summary Autophagy is the capability of cells to dismantle and recycle parts of
themselves. This process is closely intertwined with other crucial cell functions, such as …

Tumour relapse, chemotherapy resistance, and metastasis continue to be unsolved issues
in cancer therapy. A recent approach has been to scrutinise drugs used in the clinic for other …

Background Current treatment recommendations for resectable or borderline pancreatic
carcinoma support upfront surgery and adjuvant therapy. However, neoadjuvant therapy …

Uncontrolled autophagy has been associated with the development and progression of
various cancers that are resistant to cancer therapy. Therefore, many efforts to modulate …

Introduction Chemotherapy eliminates most of the cancer cells except those with potential
for self-renewal and tumor initiation, called cancer stem cells (CSCs). Chloroquine, through …

Pancreatic ductal adenocarcinoma (PDAC) remains an extremely aggressive disease
characterized by rapidly acquired multi-drug resistance, including to first-line …