Oxymatrine (OMT), was identified as a quinolizidine alkaloid, which was one of the major
matrine-type alkaloids extracted from Sophora medicinal plants. Growing studies revealed …

The contribution of natural products (NPs) to cardiovascular medicine has been extensively
documented, and many have been used for centuries. Cardiovascular disease (CVD) is the …

Abstract Background/Aims: Doxorubicin-induced cardiac toxicity has been a major concern
of oncologists and is considered the main restriction on its clinical application. Oxymatrine …

Oxymatrine (OMT) is a quinolizidine alkaloid derived from the roots of the Sophora genus
plants. It has been widely used as a treatment for chronic hepatitis infections and …

Neonatal hypoxic–ischaemic brain damage is a leading cause of child mortality and
morbidity, including cerebral palsy, epilepsy, and cognitive disabilities. The majority of …

Matrine, an active constituent of the Chinese herb, Sophora flavescens Ait., and it is known
for its antioxidant, anti-inflammatory and antitumor activities. It has been demonstrated that …

Oxymatrine is a traditional Chinese herbal product that exhibits anti-inflammatory effects in
models of heart, brain and liver injury. We investigated the impact of oxymatrine in an acute …

Cardiovascular diseases (CVDs) are the result of complex pathophysiological processes in
the tissues comprising the heart and blood vessels. Inflammation is the main culprit for the …

Background: Ovarian cancer is the most lethal gynecological malignancy, and
chemotherapy remains the cornerstone for ovarian cancer management. Due to the …

Oxymatrine (OMT), an active constituent of Chinese herb Sophora flavescens Ait, has been
proved to possess anti-tumor, anti-oxidant, anti-inflammatory, and anti-apoptotic activities …