Connectomics and epilepsy

J Engel, PM Thompson, JM Stern… - Current opinion in …, 2013 - journals.lww.com
An understanding of the fundamental mechanisms underlying the development of epilepsy
and the generation of epileptic seizures will require delineation of the aberrant functional …

Connectomics and graph theory analyses: novel insights into network abnormalities in epilepsy

E Gleichgerrcht, M Kocher, L Bonilha - Epilepsia, 2015 - Wiley Online Library
The assessment of neural networks in epilepsy has become increasingly relevant in the
context of translational research, given that localized forms of epilepsy are more likely to be …

Motor system hyperconnectivity in juvenile myoclonic epilepsy: a cognitive functional magnetic resonance imaging study

C Vollmar, J O'Muircheartaigh, GJ Barker, MR Symms… - Brain, 2011 - academic.oup.com
Juvenile myoclonic epilepsy is the most frequent idiopathic generalized epilepsy syndrome.
It is characterized by predominant myoclonic jerks of upper limbs, often provoked by …

Abnormal thalamocortical structural and functional connectivity in juvenile myoclonic epilepsy

J O'Muircheartaigh, C Vollmar, GJ Barker, V Kumari… - Brain, 2012 - academic.oup.com
Juvenile myoclonic epilepsy is the most common idiopathic generalized epilepsy,
characterized by frequent myoclonic jerks, generalized tonic-clonic seizures and, less …

Diffusion tensor imaging in temporal lobe epilepsy

DW Gross - Epilepsia, 2011 - Wiley Online Library
Although mesial temporal sclerosis (MTS) has long been recognized in association with
temporal lobe epilepsy (TLE), there is a growing body of literature suggesting structural …

Dynamics on networks: the role of local dynamics and global networks on the emergence of hypersynchronous neural activity

H Schmidt, G Petkov, MP Richardson… - PLoS computational …, 2014 - journals.plos.org
Graph theory has evolved into a useful tool for studying complex brain networks inferred
from a variety of measures of neural activity, including fMRI, DTI, MEG and EEG. In the study …

Structural connections of the centromedian nucleus of thalamus and their relevance for neuromodulation in generalized drug-resistant epilepsy: insight from a …

LG Remore, Z Rifi, H Nariai… - Therapeutic …, 2023 - journals.sagepub.com
Background: Epilepsy is a widespread neurologic disorder and almost one-third of patients
suffer from drug-resistant epilepsy (DRE). Neuromodulation targeting the …

Photosensitivity in generalized epilepsies

S Poleon, JP Szaflarski - Epilepsy & Behavior, 2017 - Elsevier
Photosensitivity, which is the hallmark of photosensitive epilepsy (PSE), is described as an
abnormal EEG response to visual stimuli known as a photoparoxysmal response (PPR). The …

Epilepsy and the frontal lobes

J O'Muircheartaigh, MP Richardson - Cortex, 2012 - Elsevier
Although the frontal lobes contain a large proportion of the total cerebral cortex in human
brain, the epilepsies arising in this region are less studied and less well characterised than …

Sex differences in human epilepsy

I Savic - Experimental Neurology, 2014 - Elsevier
In the majority of neuropsychiatric conditions, marked gender-based differences have been
found in the epidemiology, clinical manifestations, and therapy of disease. Emerging data …