[HTML][HTML] Interactome-based approaches to human disease
M Caldera, P Buphamalai, F Müller… - Current Opinion in Systems …, 2017 - Elsevier
Recent advances in high-throughput technologies have created exciting opportunities for
systematically investigating the molecular basis of human disease. In addition to a growing …
systematically investigating the molecular basis of human disease. In addition to a growing …
[HTML][HTML] Predicting lncRNA–miRNA interactions based on interactome network and graphlet interaction
In the development and treatment of many human diseases, the regulatory roles between
lncRNAs and miRNAs are important, but much remains unknown about them; moreover …
lncRNAs and miRNAs are important, but much remains unknown about them; moreover …
Exploring the structure and function of temporal networks with dynamic graphlets
Y Hulovatyy, H Chen, T Milenković - Bioinformatics, 2015 - academic.oup.com
Motivation: With increasing availability of temporal real-world networks, how to efficiently
study these data? One can model a temporal network as a single aggregate static network …
study these data? One can model a temporal network as a single aggregate static network …
From homogeneous to heterogeneous network alignment via colored graphlets
S Gu, J Johnson, FE Faisal, T Milenković - Scientific reports, 2018 - nature.com
Network alignment (NA) compares networks with the goal of finding a node mapping that
uncovers highly similar (conserved) network regions. Existing NA methods are …
uncovers highly similar (conserved) network regions. Existing NA methods are …
Prediction of potential small molecule-associated microRNAs using graphlet interaction
MicroRNAs (miRNAs) have been proved to be targeted by the small molecules recently,
which made using small molecules to target miRNAs become a possible therapy for human …
which made using small molecules to target miRNAs become a possible therapy for human …
MFIDMA: a multiple information integration model for the prediction of drug–miRNA associations
Simple Summary Predicting the possible associations between drugs and miRNAs would
provide new perspectives on miRNA therapeutics research and drug discovery. However …
provide new perspectives on miRNA therapeutics research and drug discovery. However …
GIMDA: graphlet interaction‐based MiRNA‐disease association prediction
X Chen, NN Guan, JQ Li, GY Yan - Journal of cellular and …, 2018 - Wiley Online Library
MicroRNAs (miRNAs) have been confirmed to be closely related to various human complex
diseases by many experimental studies. It is necessary and valuable to develop powerful …
diseases by many experimental studies. It is necessary and valuable to develop powerful …
Integrational analysis of miRNAs data sets as a plausible missing linker between Epstein-Barr virus and vitamin D in relapsing remitting MS patients
M Teymoori-Rad, SH Mozhgani, M Zarei-Ghobadi… - Gene, 2019 - Elsevier
Given the multifactorial state of autoimmune complex diseases such as multiple sclerosis
(MS), it is not clear if different risk factors act jointly or independently. Despite intensive …
(MS), it is not clear if different risk factors act jointly or independently. Despite intensive …
Predicting disease-related genes by path structure and community structure in protein–protein networks
K Hu, JB Hu, L Tang, J Xiang, JL Ma… - Journal of Statistical …, 2018 - iopscience.iop.org
Network-based computational approaches in the prediction of genes that are associated
with diseases are of considerable importance in uncovering the molecular basis of human …
with diseases are of considerable importance in uncovering the molecular basis of human …
Identification of miRNA-small molecule associations by continuous feature representation using auto-encoders
MicroRNAs (miRNAs) are short non-coding RNAs that play important roles in the body and
affect various diseases, including cancers. Controlling miRNAs with small molecules is …
affect various diseases, including cancers. Controlling miRNAs with small molecules is …