Histone deacetylase 11 inhibition promotes breast cancer metastasis from lymph nodes

PL Leslie, YL Chao, YH Tsai, SK Ghosh… - Nature …, 2019 - nature.com
Lymph node (LN) metastases correspond with a worse prognosis in nearly all cancers, yet
the occurrence of cancer spreading from LNs remains controversial. Additionally, the …

Factors affecting sentinel node metastasis in thin (T1) cutaneous melanomas: development and external validation of a predictive nomogram

A Maurichi, R Miceli, H Eriksson… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Thin melanomas (T1;≤ 1 mm) constitute 70% of newly diagnosed cutaneous
melanomas. Regional node metastasis determined by sentinel node biopsy (SNB) is an …

Variations in persistent use of low-value breast cancer surgery

T Wang, BC Bredbeck, B Sinco, S Shubeck… - JAMA …, 2021 - jamanetwork.com
Importance Through the Choosing Wisely campaign, surgical specialties identified 4 low-
value breast cancer operations. Preliminary data suggest varying rates of deimplementation …

[HTML][HTML] Fluid mechanics in circulating tumour cells: role in metastasis and treatment strategies

S Rajput, PK Sharma, R Malviya - Medicine in Drug Discovery, 2023 - Elsevier
Cancer patients have a shorter life expectancy because of metastasis, which is the dynamic
chain of events that leads to the spread of tumour cells to distant places inside the body …

Neoadjuvant systemic therapy (NAST) in patients with melanoma: surgical considerations by the International Neoadjuvant Melanoma Consortium (INMC)

ACJ van Akkooi, TJ Hieken, EM Burton… - Annals of surgical …, 2022 - Springer
Exciting advances in melanoma systemic therapies have presented the opportunity for
surgical oncologists and their multidisciplinary colleagues to test the neoadjuvant systemic …

Guidance of sentinel lymph node biopsy decisions in patients with T1–T2 melanoma using gene expression profiling

JT Vetto, EC Hsueh, BR Gastman, LD Dillon… - Future …, 2019 - Taylor & Francis
Aim: Can gene expression profiling be used to identify patients with T1–T2 melanoma at low
risk for sentinel lymph node (SLN) positivity? Patients & methods: Bioinformatics modeling …

Metastatic status of sentinel lymph nodes in breast cancer determined with photoacoustic microscopy via dual-targeting nanoparticles

Y Dai, X Yu, J Wei, F Zeng, Y Li, X Yang… - Light: Science & …, 2020 - nature.com
Detection of sentinel lymph nodes (SLNs) is critical to guide the treatment of breast cancer.
However, distinguishing metastatic SLNs from normal and inflamed lymph nodes (LNs) …

Multi-scale characterization of tumor-draining lymph nodes in resectable lung cancer treated with neoadjuvant immune checkpoint inhibitors

H Yang, B Sun, W Ma, L Fan, K Xu, Y Jia, J Xu… - …, 2022 - thelancet.com
Background Regional lymph node (LN) acts as a pivotal organ for antitumor immunity.
Paradoxically, tumor-draining LNs (TDLNs) are usually the first site of tumor metastasis in …

Unexpected contribution of lymphatic vessels to promotion of distant metastatic tumor spread

Q Ma, LC Dieterich, K Ikenberg, SB Bachmann… - Science …, 2018 - science.org
Tumor lymphangiogenesis is accompanied by a higher incidence of sentinel lymph node
metastasis and shorter overall survival in several types of cancer. We asked whether tumor …

Anatomic region of cutaneous melanoma impacts survival and clinical outcomes: a population-based analysis

CM Shannon, NK Mehta, H Li, SA Nguyen… - Cancers, 2023 - mdpi.com
Simple Summary Despite the increasing incidence of melanoma in the United States, few
studies have compared tumor and clinical characteristics of cutaneous melanoma by …