Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice

SY Jiao, YH Yang, SR Chen - Human reproduction update, 2021 - academic.oup.com
BACKGROUND Infertility is a major issue in human reproductive health, affecting an
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …

Sperm DNA damage caused by oxidative stress: modifiable clinical, lifestyle and nutritional factors in male infertility

C Wright, S Milne, H Leeson - Reproductive biomedicine online, 2014 - Elsevier
DNA fragmentation is an important factor in the aetiology of male infertility. However, it is still
underevaluated and its inclusion in routine semen analysis is debated. DNA fragmentation …

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities

J Bosteels, J Kasius, S Weyers… - Cochrane Database …, 2015 - cochranelibrary.com
Background Observational studies suggest higher pregnancy rates after the hysteroscopic
removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine …

[HTML][HTML] The effect of sperm DNA fragmentation index on assisted reproductive technology outcomes and its relationship with semen parameters and lifestyle

H Yang, G Li, H Jin, Y Guo, Y Sun - Translational andrology and …, 2019 - ncbi.nlm.nih.gov
Background The sperm DNA fragmentation index (DFI) is widely regarded as a key measure
for assessing male fertility, but the predictive value of the DFI for outcomes of assisted …

Female subfertility

CM Farquhar, S Bhattacharya, S Repping… - Nature reviews Disease …, 2019 - nature.com
Subfertility is common and affects one in six couples, half of whom lack an explanation for
their delay in conceiving. Developments in the diagnosis and treatment of subfertility over …

Female infertility

RL Barbieri - Yen and Jaffe's reproductive endocrinology, 2019 - Elsevier
Infertility affects approximately 13% of women and 10% of men. The major causes of female
infertility are anovulation, fallopian tube disease, pelvic adhesions, endometriosis, and …

[HTML][HTML] Thoughts on the popularity of ICSI

M Haddad, J Stewart, P Xie, S Cheung, A Trout… - Journal of assisted …, 2021 - Springer
Purpose Intracytoplasmic sperm injection (ICSI) is the most widely utilized assisted
reproductive technique (ART) worldwide. In this feature, we review the early assisted …

[PDF][PDF] 辅助生殖促排卵药物治疗专家共识

乔杰, 马彩虹, 刘嘉茵, 马翔, 李尚为, 杨业洲… - 生殖与 …, 2015 - medi-guide.meditool.cn
辅助生殖技术(ART) 的重要内容之一是促排卵治疗, 其应用改善了临床妊娠率, 但多胎妊娠,
卵巢过度刺激综合征(OHSS) 等并发症发生几率较高. 促排卵最常用药物为克罗米芬(CC) …

[HTML][HTML] Sedentary behavior, physical inactivity and body composition in relation to idiopathic infertility among men and women

AM Foucaut, C Faure, C Julia, S Czernichow, R Levy… - PloS one, 2019 - journals.plos.org
Background Physical activity (PA) and sedentary behavior have inconsistent effects on
fertility. High body mass index is associated with infertility but to our knowledge, very few …

Oocyte activation deficiency and assisted oocyte activation: mechanisms, obstacles and prospects for clinical application

J Kashir, D Ganesh, C Jones… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Oocyte activation deficiency (OAD) is attributed to the majority of cases
underlying failure of ICSI cycles, the standard treatment for male factor infertility. Oocyte …