[HTML][HTML] Single-cell transcriptomics allows novel insights into the endocrine-disrupting chemicals induced mammalian reproductive disorder
TR He, HX Liu, G Zhang, L Li, W Shen, W Ge - … and Environmental Safety, 2023 - Elsevier
Increasing environmental pollution has led to the spread of many endocrine-disrupting
chemicals (EDCs) around the world, which are toxic substances in the form of compounds …
chemicals (EDCs) around the world, which are toxic substances in the form of compounds …
Maternal exposure to dibutyl phthalate regulates MSH6 crotonylation to impair homologous recombination in fetal oocytes
Y Ma, X Mu, R Gao, Y Zhang, Y Geng, X Chen… - Journal of Hazardous …, 2023 - Elsevier
Homologous recombination (HR) during early oogenesis repairs programmed double-
strand breaks (DSBs) to ensure female fertility and offspring health. The exposure of fetal …
strand breaks (DSBs) to ensure female fertility and offspring health. The exposure of fetal …
Inter-and trans-generational impacts of environmental exposures on the germline resolved at the single-cell level
Reproduction is a remarkably intricate process involving the interaction of multiple cell types
and organ systems unfolding over long periods of time and that culminates with the …
and organ systems unfolding over long periods of time and that culminates with the …
[HTML][HTML] Identification of phthalate mixture exposure targets in the human and mouse ovary in vitro
I Tarvainen, DA Soto, MJ Laws, RD Björvang… - Reproductive …, 2023 - Elsevier
Chemical health risk assessment is based on single chemicals, but humans and wildlife are
exposed to extensive mixtures of industrial substances and pharmaceuticals. Such …
exposed to extensive mixtures of industrial substances and pharmaceuticals. Such …
Mechanisms of imbalanced testicular homeostasis in infancy due to aberrant histone acetylation in undifferentiated spermatogonia under different concentrations of Di …
Y Tian, J Guo, L Hua, Y Jiang, W Ge, X Zhang… - Environmental …, 2024 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP), identified as an endocrine-disrupting chemical,
is associated with reproductive toxicity. This association is particularly noteworthy in …
is associated with reproductive toxicity. This association is particularly noteworthy in …
Naringin regulates intestinal microorganisms and serum metabolites to promote spermatogenesis
PY Dong, SL Liang, L Li, J Liu, SE Zhang, FG Klinger… - Food & Function, 2023 - pubs.rsc.org
Naringin (NAR) is a dihydroflavonoid with various biological activities and pharmacological
effects, especially natural antioxidant activity. To gain a better understanding of the effects of …
effects, especially natural antioxidant activity. To gain a better understanding of the effects of …
[HTML][HTML] Novel Insight into the mechanism of di (2-ethylhexyl) phthalate (DEHP) impairing early follicle development
M Feng, J Wang, X Zhao, H Du, Y Dai - Ecotoxicology and Environmental …, 2024 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP), an artificially synthetic plasticizer, is a
widespread environmental endocrine disruptor, which has raised substantial concern …
widespread environmental endocrine disruptor, which has raised substantial concern …