Hyphal growth in human fungal pathogens and its role in virulence
A Brand - International journal of microbiology, 2012 - Wiley Online Library
Most of the fungal species that infect humans can grow in more than one morphological form
but only a subset of pathogens produce filamentous hyphae during the infection process …
but only a subset of pathogens produce filamentous hyphae during the infection process …
Aspergillus‐Associated Airway Disease, Inflammation, and the Innate Immune Response
SH Chotirmall, M Al-Alawi, B Mirkovic… - BioMed research …, 2013 - Wiley Online Library
Aspergillus moulds exist ubiquitously as spores that are inhaled in large numbers daily.
Whilst most are removed by anatomical barriers, disease may occur in certain …
Whilst most are removed by anatomical barriers, disease may occur in certain …
Evolutionary compromises in fungal fitness: hydrophobins can hinder the adverse dispersal of conidiospores and challenge their survival
F Cai, R Gao, Z Zhao, M Ding, S Jiang, C Yagtu… - The ISME …, 2020 - academic.oup.com
Fungal evolutionary biology is impeded by the scarcity of fossils, irregular life cycles,
immortality, and frequent asexual reproduction. Simple and diminutive bodies of fungi …
immortality, and frequent asexual reproduction. Simple and diminutive bodies of fungi …
Human NK cells display important antifungal activity against Aspergillus fumigatus, which is directly mediated by IFN-γ release
M Bouzani, M Ok, A McCormick, F Ebel… - The Journal of …, 2011 - journals.aai.org
Despite the strong interest in the NK cell-mediated immunity toward malignant cells and
viruses, there is a relative lack of data on the interplay between NK cells and filamentous …
viruses, there is a relative lack of data on the interplay between NK cells and filamentous …
Combination therapy to treat fungal biofilm-based infections
J Tits, BPA Cammue, K Thevissen - International Journal of Molecular …, 2020 - mdpi.com
An increasing number of people is affected by fungal biofilm-based infections, which are
resistant to the majority of currently-used antifungal drugs. Such infections are often caused …
resistant to the majority of currently-used antifungal drugs. Such infections are often caused …
Virulence determinants of the human pathogenic fungus Aspergillus fumigatus protect against soil amoeba predation
F Hillmann, S Novohradská, DJ Mattern… - Environmental …, 2015 - Wiley Online Library
Filamentous fungi represent classical examples for environmentally acquired human
pathogens whose major virulence mechanisms are likely to have emerged long before the …
pathogens whose major virulence mechanisms are likely to have emerged long before the …
Galleria mellonella as a model system to study virulence potential of mucormycetes and evaluation of antifungal treatment
Mucorales can cause cutaneous to deep-seated infections, mainly in the
immunocompromised host, resulting in high mortality rates due to late and inefficient …
immunocompromised host, resulting in high mortality rates due to late and inefficient …
The eukaryome: diversity and role of microeukaryotic organisms associated with animal hosts
Awareness of the roles that host‐associated microbes play in host biology has escalated in
recent years. However, microbiome studies have focused essentially on bacteria, and …
recent years. However, microbiome studies have focused essentially on bacteria, and …
Interaction of the pathogenic mold Aspergillus fumigatus with lung epithelial cells
N Osherov - Frontiers in microbiology, 2012 - frontiersin.org
Aspergillus fumigatus is an opportunistic environmental mold that can cause severe allergic
responses in atopic individuals and poses a life-threatening risk for severely …
responses in atopic individuals and poses a life-threatening risk for severely …
Characterization of the velvet regulators in Aspergillus fumigatus
Fungal development and secondary metabolism is intimately associated via activities of the
fungi‐specific velvet family proteins. Here we characterize the four velvet regulators in the …
fungi‐specific velvet family proteins. Here we characterize the four velvet regulators in the …