Oxidative stress, inflammation and hormesis: The role of dietary and lifestyle modifications on aging

V Sharma, MM Mehdi - Neurochemistry international, 2023 - Elsevier
Oxidative stress (OS) is primarily caused by the formation of free radicals and reactive
oxygen species; it is considered as one of the prominent factors in slowing down and …

The active grandparent hypothesis: Physical activity and the evolution of extended human healthspans and lifespans

DE Lieberman, TM Kistner, D Richard… - Proceedings of the …, 2021 - National Acad Sciences
The proximate mechanisms by which physical activity (PA) slows senescence and
decreases morbidity and mortality have been extensively documented. However, we lack an …

The gut barrier, intestinal microbiota, and liver disease: molecular mechanisms and strategies to manage

J Plaza-Díaz, P Solís-Urra… - International journal of …, 2020 - mdpi.com
Liver disease encompasses pathologies as non-alcoholic fatty liver disease, non-alcoholic
steatohepatitis, alcohol liver disease, hepatocellular carcinoma, viral hepatitis, and …

Molecular mechanisms underlying the beneficial effects of exercise on brain function and neurological disorders

K Nay, WJ Smiles, J Kaiser, LM McAloon, K Loh… - International Journal of …, 2021 - mdpi.com
As life expectancy has increased, particularly in developed countries, due to medical
advances and increased prosperity, age-related neurological diseases and mental health …

Exercise-induced irisin decreases inflammation and improves NAFLD by competitive binding with MD2

W Zhu, NE Sahar, HMA Javaid, ES Pak, G Liang… - Cells, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a global clinical problem. The MD2-TLR4
pathway exacerbates NAFLD progression by promoting inflammation. Long-term exercise is …

The athlete gut microbiome and its relevance to health and performance: a review

MT O'Brien, O O'Sullivan, MJ Claesson, PD Cotter - Sports Medicine, 2022 - Springer
The human gut microbiome is a complex ecosystem of microorganisms that play an
important role in human health, influencing functions such as vitamin uptake, digestion and …

Is there an exercise-intensity threshold capable of avoiding the leaky gut?

FM Ribeiro, B Petriz, G Marques, LH Kamilla… - Frontiers in …, 2021 - frontiersin.org
Endurance-sport athletes have a high incidence of gastrointestinal disorders, compromising
performance and impacting overall health status. An increase in several proinflammatory …

Exploring the gut microbiota: lifestyle choices, disease associations, and personal genomics

S Pedroza Matute, S Iyavoo - Frontiers in Nutrition, 2023 - frontiersin.org
The gut microbiota is a rich and dynamic ecosystem that actively interacts with the human
body, playing a significant role in the state of health and disease of the host. Diet, exercise …

[HTML][HTML] The effect of eight weeks resistance and endurance training on some angiogenesis factors of hippocampus tissue in male wistar rats

M Sadegh Ghomi, M Kashef… - Journal of Sport and …, 2021 - joeppa.sbu.ac.ir
Purpose: One of the cause of adaptations due to exercise training is increased capillary
density or angiogenesis. increased blood flow to hippocampus tissue causes improvement …

Examining the Interaction between Exercise, Gut Microbiota, and neurodegeneration: future research directions

D Rojas-Valverde, DA Bonilla, LM Gómez-Miranda… - Biomedicines, 2023 - mdpi.com
Physical activity has been demonstrated to have a significant impact on gut microbial
diversity and function. Emerging research has revealed certain aspects of the complex …