[HTML][HTML] Physical Exercise as Disease-Modifying Alternative against Alzheimer's Disease: A Gut–Muscle–Brain Partnership
D Cutuli, D Decandia, G Giacovazzo… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a common cause of dementia characterized by
neurodegenerative dysregulations, cognitive impairments, and neuropsychiatric symptoms …
neurodegenerative dysregulations, cognitive impairments, and neuropsychiatric symptoms …
[HTML][HTML] Therapeutic potential of targeting mitochondria for Alzheimer's disease treatment
Alzheimer's disease (AD), a chronic and progressive neurodegenerative disease, is
characterized by memory and cognitive impairment and by the accumulation in the brain of …
characterized by memory and cognitive impairment and by the accumulation in the brain of …
[HTML][HTML] Pre-and post-treatment of α-Tocopherol on cognitive, synaptic plasticity, and mitochondrial disorders of the hippocampus in icv-streptozotocin-induced …
F Nabavi Zadeh, M Nazari, A Amini, S Adeli… - Frontiers in …, 2023 - frontiersin.org
Objective Most dementia cases in the elderly are caused by Alzheimer's disease (AD), a
complex, progressive neurological disease. Intracerebroventricular (ICV) administration of …
complex, progressive neurological disease. Intracerebroventricular (ICV) administration of …
Pathological impact of tau proteolytical process on neuronal and mitochondrial function: a crucial role in alzheimer's disease
MA Olesen, RA Quintanilla - Molecular Neurobiology, 2023 - Springer
Tau protein plays a pivotal role in the central nervous system (CNS), participating in
microtubule stability, axonal transport, and synaptic communication. Research interest has …
microtubule stability, axonal transport, and synaptic communication. Research interest has …
Cdc42GAP deficiency contributes to the Alzheimer's disease phenotype
M Zhu, B Xiao, T Xue, S Qin, J Ding, Y Wu, Q Tang… - Brain, 2023 - academic.oup.com
Alzheimer's disease, the most common cause of dementia, is a chronic degenerative
disease with typical pathological features of extracellular senile plaques and intracellular …
disease with typical pathological features of extracellular senile plaques and intracellular …
Early time course of oxidative stress in hippocampal synaptosomes and cognitive loss following impaired insulin signaling in rats: Development of sporadic …
Oxidative stress, caused by impaired insulin signaling, plays a pivotal role in the
pathogenesis of sporadic Alzheimer's disease (sAD). We investigated the oxidative stress …
pathogenesis of sporadic Alzheimer's disease (sAD). We investigated the oxidative stress …
[HTML][HTML] Impaired insulin signaling alters mediators of hippocampal synaptic dynamics/plasticity: a possible mechanism of hyperglycemia-induced cognitive …
Simple Summary An early time course study of the proteins associated to synaptic dynamics
and cognitive behavior. Study evaluated the expression levels and activation state of …
and cognitive behavior. Study evaluated the expression levels and activation state of …
Cognitive dysfunction and increased phosphorylated tau are associated with reduced O‐GlcNAc signaling in an aging mouse model of metabolic syndrome
Metabolic syndrome (MetS), characterized by hyperglycemia, obesity, and hyperlipidemia,
can increase the risk of developing late‐onset dementia. Recent studies in patients and …
can increase the risk of developing late‐onset dementia. Recent studies in patients and …
[HTML][HTML] Peroxiredoxin 1 inhibits streptozotocin-induced Alzheimer's disease-like pathology in hippocampal neuronal cells via the blocking of Ca2+/Calpain/Cdk5 …
J Park, J Won, E Yang, J Seo, J Cho, JB Seong… - Scientific Reports, 2024 - nature.com
Oxidative stress plays an essential role in the progression of Alzheimer's disease (AD), the
most common age-related neurodegenerative disorder. Streptozotocin (STZ)-induced …
most common age-related neurodegenerative disorder. Streptozotocin (STZ)-induced …
[HTML][HTML] Shen Qi Wan ameliorates learning and memory impairment induced by STZ in AD rats through PI3K/AKT pathway
J Huang, Z Xu, H Chen, Y Lin, J Wei, S Wang, H Yu… - Brain Sciences, 2022 - mdpi.com
Alzheimer's disease is the most common form of neurodegenerative disease, and increasing
evidence shows that insulin signaling has crucial roles in AD initiation and progression. In …
evidence shows that insulin signaling has crucial roles in AD initiation and progression. In …