Evaluation of antifungal use in a tertiary care institution: antifungal stewardship urgently needed
M Valerio, CG Rodriguez-Gonzalez… - Journal of …, 2014 - academic.oup.com
Objectives To assess the quality of antifungal use, to propose a point score for this
evaluation and to estimate the potential economic savings of an antifungal stewardship …
evaluation and to estimate the potential economic savings of an antifungal stewardship …
A randomized, placebo-controlled trial of preemptive antifungal therapy for the prevention of invasive candidiasis following gastrointestinal surgery for intra-abdominal …
W Knitsch, JL Vincent, S Utzolino… - Clinical Infectious …, 2015 - academic.oup.com
Background. Patients undergoing emergency gastrointestinal surgery for intra-abdominal
infection are at risk of invasive candidiasis (IC) and candidates for preemptive antifungal …
infection are at risk of invasive candidiasis (IC) and candidates for preemptive antifungal …
(1,3)-β-d-Glucan-based empirical antifungal interruption in suspected invasive candidiasis: a randomized trial
Abstract Background (1, 3)-β-d-Glucan has been widely used in clinical practice for the
diagnosis of invasive Candida infections. However, such serum biomarker showed potential …
diagnosis of invasive Candida infections. However, such serum biomarker showed potential …
Candida spp. airway colonization could promote antibiotic-resistant bacteria selection in patients with suspected ventilator-associated pneumonia
M Hamet, A Pavon, F Dalle, A Pechinot, S Prin… - Intensive care …, 2012 - Springer
Objective Candida spp. airway colonization could promote development of ventilator-
associated pneumonia (VAP) caused by Pseudomonas aeruginosa, a potentially multidrug …
associated pneumonia (VAP) caused by Pseudomonas aeruginosa, a potentially multidrug …
β-D-glucan surveillance with preemptive anidulafungin for invasive candidiasis in intensive care unit patients: a randomized pilot study
KE Hanson, CD Pfeiffer, ED Lease, AH Balch, AK Zaas… - 2012 - journals.plos.org
Background Invasive candidiasis (IC) is a devastating disease. While prompt antifungal
therapy improves outcomes, empiric treatment based on the presence of fever has little …
therapy improves outcomes, empiric treatment based on the presence of fever has little …
Non-culture diagnostics for invasive candidiasis: promise and unintended consequences
CJ Clancy, MH Nguyen - Journal of Fungi, 2018 - mdpi.com
Blood cultures are positive for Candida species in< 50% and< 20% of hematogenously
disseminated and intra-abdominal candidiasis, respectively. Non-culture tests such as …
disseminated and intra-abdominal candidiasis, respectively. Non-culture tests such as …
A prospective clinical trial of a real-time polymerase chain reaction assay for the diagnosis of candidemia in nonneutropenic, critically ill adults
R McMullan, L Metwally, PV Coyle… - Clinical infectious …, 2008 - academic.oup.com
Abstract Background. Invasive Candida infection among nonneutropenic, critically ill adults
is a clinical problem that has received increasing attention in recent years. Poor …
is a clinical problem that has received increasing attention in recent years. Poor …
Evaluation of "Candida score" in critically ill patients: a prospective, multicenter, observational, cohort study
G Leroy, F Lambiotte, D Thévenin, C Lemaire… - Annals of intensive …, 2011 - Springer
Introduction Although prompt initiation of appropriate antifungal therapy is essential for the
control of invasive Candida infections and an improvement of prognosis, early diagnosis of …
control of invasive Candida infections and an improvement of prognosis, early diagnosis of …
Inappropriate empiric antifungal therapy for candidemia in the ICU and hospital resource utilization: a retrospective cohort study
MD Zilberberg, MH Kollef, H Arnold, A Labelle… - BMC infectious …, 2010 - Springer
Background Candida represents the most common cause of invasive fungal disease, and
candidal blood stream infections (CBSI) are prevalent in the ICU. Inappropriate antifungal …
candidal blood stream infections (CBSI) are prevalent in the ICU. Inappropriate antifungal …
Fungal diagnosis: how do we do it and can we do better?
JR Perfect - Current medical research and opinion, 2013 - Taylor & Francis
Background: Morbidity and mortality remain high for patients with invasive fungal infections
(IFIs) despite an increasing number of antifungals and other treatments. Many studies …
(IFIs) despite an increasing number of antifungals and other treatments. Many studies …