INTRODUCTION: Accumulating evidence suggests that patients with type 2 diabetes
mellitus (T2DM) and hyperinsulinemia are at increased risk for developing malignancies. It …

Effects of Sulfonylureas on Tumor Growth: A Review of the Literature | The Oncologist | Oxford
Academic Skip to Main Content Advertisement Oxford Academic Journals Books Search Menu …

This study was aimed at the assessment of incidence of malignancies in type 2 diabetic
patients treated with different sulphonylureas. A matched case–control study was performed …

Aims Cisplatin (CP), as an effective alkylating agent, is widely used in cancer treatment,
while hepatotoxicity is one of its side effects. Gliclazide (GLZ), as an oral hypoglycemic drug …

摘要糖尿病与肿瘤都是异质性的多因素疾病, 严重影响全球人类健康. 流行病学证据揭示,
某些恶性肿瘤与糖尿病, 糖尿病危险因素和某些降糖药物密切相关. 多种生物学机制可以解释 …

BACKGROUND: Hyperglycaemia is a risk factor for cancer and some sulphonylureas have
anti-oxidant properties. This study examined associations between use of sulphonylureas …

Cisplatin (CP), as a chemotherapeutic drug, causes nephrotoxicity that has limited the
clinical utility of CP. Gliclazide (GLZ), as an antihyperglycemic drug, at low dose has …

Type 2 diabetes mellitus is associated with elevated level of oxidative stress, which is one of
the most important factors responsible for the development of chronic complications of this …

Background To evaluate whether anti-diabetic medications are related to colorectal cancer
(CRC) risk in type 2 diabetes patients. Methods The study was performed from a population …

Gliclazide is a second-generation oral hypoglycemic drug used for the treatment of
noninsulin-dependent diabetes mellitus. It belongs to the sulfonylurea class that stimulates …