External validation of deep learning algorithms for radiologic diagnosis: a systematic review
Purpose To assess generalizability of published deep learning (DL) algorithms for radiologic
diagnosis. Materials and Methods In this systematic review, the PubMed database was …
diagnosis. Materials and Methods In this systematic review, the PubMed database was …
[HTML][HTML] Evidence-based pharmacological treatment options for ADHD in children and adolescents
K Mechler, T Banaschewski, S Hohmann… - Pharmacology & …, 2022 - Elsevier
Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder
characterized by inattention, hyperactivity, and impulsivity, causing functional impairment. Its …
characterized by inattention, hyperactivity, and impulsivity, causing functional impairment. Its …
Digitizing clinical trials
OT Inan, P Tenaerts, SA Prindiville, HR Reynolds… - NPJ digital …, 2020 - nature.com
Clinical trials are a fundamental tool used to evaluate the efficacy and safety of new drugs
and medical devices and other health system interventions. The traditional clinical trials …
and medical devices and other health system interventions. The traditional clinical trials …
A review of generalizability and transportability
When assessing causal effects, determining the target population to which the results are
intended to generalize is a critical decision. Randomized and observational studies each …
intended to generalize is a critical decision. Randomized and observational studies each …
Depressive symptoms and depression in individuals with internet gaming disorder: A systematic review and meta-analysis
EG Ostinelli, C Zangani, B Giordano, D Maestri… - Journal of affective …, 2021 - Elsevier
Background Although depression has frequently been associated with Internet Gaming
Disorder (IGD), its epidemiological impact on this emerging condition has not been …
Disorder (IGD), its epidemiological impact on this emerging condition has not been …
Evaluating digital health interventions: key questions and approaches
Digital health interventions have enormous potential as scalable tools to improve health and
healthcare delivery by improving effectiveness, efficiency, accessibility, safety, and …
healthcare delivery by improving effectiveness, efficiency, accessibility, safety, and …
Dropout rates of in‐person psychosocial substance use disorder treatments: a systematic review and meta‐analysis
Abstract Background and Aims Relapse rates for psychosocial substance use disorder
(SUD) treatments are high, and dropout is a robust predictor of relapse. This study aimed to …
(SUD) treatments are high, and dropout is a robust predictor of relapse. This study aimed to …
Low-density lipoprotein cholesterol reduction and statin intensity in myocardial infarction patients and major adverse outcomes: a Swedish nationwide cohort study
J Schubert, B Lindahl, H Melhus… - European heart …, 2021 - academic.oup.com
Aims Clinical trials have demonstrated that a reduction in low-density lipoprotein cholesterol
(LDL-C) reduces cardiovascular (CV) events. This has, however, not yet been shown in a …
(LDL-C) reduces cardiovascular (CV) events. This has, however, not yet been shown in a …
Quality of life is substantially worse for community-dwelling older people living with frailty: systematic review and meta-analysis
TF Crocker, L Brown, A Clegg, K Farley… - Quality of Life …, 2019 - Springer
Purpose Frailty is an important predictor of adverse health events in older people, and
improving quality of life (QOL) is increasingly recognised as a focus for services in this …
improving quality of life (QOL) is increasingly recognised as a focus for services in this …
Representation and outcomes of individuals with schizophrenia seen in everyday practice who are ineligible for randomized clinical trials
H Taipale, J Schneider-Thoma… - JAMA …, 2022 - jamanetwork.com
Importance Most evidence about efficacy and safety of antipsychotics in schizophrenia
spectrum disorders relies on randomized clinical trials (RCTs). However, owing to their strict …
spectrum disorders relies on randomized clinical trials (RCTs). However, owing to their strict …