New non-invasive approaches that can complement and improve on current strategies for
colorectal cancer (CRC) screening and management are urgently needed. A growing …

Circulating tumor cells (CTCs) shed from primary and metastatic cancers are admixed with
blood components and are thus rare, making their isolation and characterization a major …

Despite considerable advancements that shattered previously held dogmas about the
metastatic cascade, the evolution of therapies to treat metastatic disease has not kept up. In …

Purpose: The development of tumor-specific markers to select targeted therapies and to
assess clinical outcome remains a significant area of unmet need. We evaluated the …

The release of circulating tumor cells (CTCs) into vasculature is an early event in the
metastatic process. The analysis of CTCs in patients has recently received widespread …

Increasing evidence suggests that circulating tumour cells (CTCs) are responsible for
metastatic relapse and this has fuelled interest in their detection and quantification. Although …

BACKGROUND & AIMS: The prognostic significance of circulating (CTCs) and disseminated
tumor cells in patients with colorectal cancer (CRC) is controversial. We performed a meta …

BACKGROUND Detection of circulating tumor cells (CTCs) in the peripheral blood is a
rapidly developing research field with clear clinical implications for the staging and …

Liquid biopsy is a technology that exhibits potential to detect cancer early, monitor therapies,
and predict cancer prognosis due to its unique characteristics, including noninvasive …

The measurement and characterization of circulating tumor cells (CTCs) hold promise for
advancing personalized therapeutics. CTCs are the precursor to metastatic cancer and thus …