Structural aspects of chemical modifications in the MHC-restricted immunopeptidome; Implications for immune recognition
T Sandalova, BM Sala, A Achour - Frontiers in Chemistry, 2022 - frontiersin.org
Significant advances in mass-spectroscopy (MS) have made it possible to investigate the
cellular immunopeptidome, a large collection of MHC-associated epitopes presented on the …
cellular immunopeptidome, a large collection of MHC-associated epitopes presented on the …
Diphthamide–a conserved modification of eEF2 with clinical relevance
R Schaffrath, U Brinkmann - Trends in Molecular Medicine, 2024 - cell.com
Diphthamide, a complex modification on eukaryotic translation elongation factor 2 (eEF2),
assures reading-frame fidelity during translation. Diphthamide and enzymes for its synthesis …
assures reading-frame fidelity during translation. Diphthamide and enzymes for its synthesis …
Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication
S Krieg, F Pott, L Potthoff, M Verheirstraeten… - Cellular and Molecular …, 2023 - Springer
Replication of viruses requires interaction with host cell factors and repression of innate
immunity. Recent findings suggest that a subset of intracellular mono-ADP-ribosylating …
immunity. Recent findings suggest that a subset of intracellular mono-ADP-ribosylating …
Mutational analysis of structural proteins of SARS-CoV-2
SARS-CoV-2 transmissibility is higher than that of other human coronaviruses; therefore, it
poses a threat to the populated communities. We investigated mutations among envelope …
poses a threat to the populated communities. We investigated mutations among envelope …
Network-based analysis of OMICs data to understand the HIV–host interaction
S Ivanov, A Lagunin, D Filimonov… - Frontiers in …, 2020 - frontiersin.org
The interaction of human immunodeficiency virus with human cells is responsible for all
stages of the viral life cycle, from the infection of CD4+ cells to reverse transcription …
stages of the viral life cycle, from the infection of CD4+ cells to reverse transcription …
Post-translational modifications of retroviral HIV-1 gag precursors: an overview of their biological role
C Bussienne, R Marquet, JC Paillart… - International Journal of …, 2021 - mdpi.com
Protein post-translational modifications (PTMs) play key roles in eukaryotes since they finely
regulate numerous mechanisms used to diversify the protein functions and to modulate their …
regulate numerous mechanisms used to diversify the protein functions and to modulate their …
HIV-1 virological synapse formation enhances infection spread by dysregulating Aurora Kinase B
JW Bruce, E Park, C Magnano, M Horswill… - PLoS …, 2023 - journals.plos.org
HIV-1 spreads efficiently through direct cell-to-cell transmission at virological synapses
(VSs) formed by interactions between HIV-1 envelope proteins (Env) on the surface of …
(VSs) formed by interactions between HIV-1 envelope proteins (Env) on the surface of …
The phosphorylation of the N protein could affect PRRSV virulence in vivo
Y Chen, Z Yu, H Yi, Y Wei, X Han, Q Li, C Ji… - Veterinary …, 2019 - Elsevier
The porcine respiratory and reproductive syndrome virus (PRRSV) nucleocapsid (N) protein
is a multiphosphorylated protein. It has been proved that the phosphorylation of N protein …
is a multiphosphorylated protein. It has been proved that the phosphorylation of N protein …
[HTML][HTML] First report of computational protein–ligand docking to evaluate susceptibility to HIV integrase inhibitors in HIV-infected Iranian patients
F Ghasabi, A Hashempour, N Khodadad… - … and Biophysics Reports, 2022 - Elsevier
Background Iran has recently included integrase (INT) inhibitors (INTIs) in the first‐line
treatment regimen in human immunodeficiency virus (HIV)-infected patients. However, there …
treatment regimen in human immunodeficiency virus (HIV)-infected patients. However, there …
[HTML][HTML] FusionAI: predicting fusion breakpoint from DNA sequence with deep learning
Identifying the molecular mechanisms related to genomic breakage is an important goal of
cancer mechanism studies. Among diverse locations of structural variants, fusion genes …
cancer mechanism studies. Among diverse locations of structural variants, fusion genes …