From molecules to morphology: cellular organization of Tetrahymena thermophila

D Wloga, J Frankel - Methods in cell biology, 2012 - Elsevier
Tetrahymena thermophila is both a cell and an organism, which combines great intracellular
complexity with a remarkable accessibility to investigation using many different approaches …

Unicellular eukaryotes as models in cell and molecular biology: critical appraisal of their past and future value

M Simon, H Plattner - International review of cell and molecular biology, 2014 - Elsevier
Unicellular eukaryotes have been appreciated as model systems for the analysis of crucial
questions in cell and molecular biology. This includes Dictyostelium (chemotaxis, amoeboid …

Ciliate research: From myth to trendsetting science

H Plattner - Journal of Eukaryotic Microbiology, 2022 - Wiley Online Library
This special issue of the Journal of Eukaryotic Microbiology (JEM) summarizes
achievements obtained by generations of researchers with ciliates in widely different …

Global and local functions of the Fused kinase ortholog CdaH in intracellular patterning in Tetrahymena

C Lee, W Maier, YY Jiang, K Nakano… - Journal of Cell …, 2024 - journals.biologists.com
Ciliates assemble numerous microtubular structures into complex cortical patterns. During
ciliate division, the pattern is duplicated by intracellular segmentation that produces a …

Membrane trafficking in protozoa: SNARE proteins, H+-ATPase, actin, and other key players in ciliates

H Plattner - International review of cell and molecular biology, 2010 - Elsevier
Due to their well-defined pathways of vesicle trafficking and manyfold mutants ciliates have
served as good model systems. Further studies required the development of databases, now …

The remembrance of the things past: conserved signalling pathways link protozoa to mammalian nervous system

H Plattner, A Verkhratsky - Cell Calcium, 2018 - Elsevier
The aim of the present article is to analyse the evolutionary links between protozoa and
neuronal and neurosecretory cells. To this effect we employ functional and topological data …

Contractile vacuole complex—its expanding protein inventory

H Plattner - International Review of Cell and Molecular Biology, 2013 - Elsevier
The contractile vacuole complex (CVC) of some protists serves for the osmotic equilibration
of water and ions, notably Ca 2+, by chemiosmotic exploitation of a H+ gradient generated …

Signalling in ciliates: long‐and short‐range signals and molecular determinants for cellular dynamics

H Plattner - Biological Reviews, 2017 - Wiley Online Library
In ciliates, unicellular representatives of the bikont branch of evolution, inter‐and
intracellular signalling pathways have been analysed mainly in Paramecium tetraurelia …

Membrane traffic and Ca2+ signals in ciliates

H Plattner - Journal of Eukaryotic Microbiology, 2022 - Wiley Online Library
A Paramecium cell has as many types of membrane interactions as mammalian cells, as
established with monoclonal antibodies by R. Allen and A. Fok. Since then, we have …

Tetrahymena thermophila: A divergent perspective on membrane traffic

JS Briguglio, AP Turkewitz - Journal of Experimental Zoology …, 2014 - Wiley Online Library
Tetrahymena thermophila, a member of the Ciliates, represents a class of organisms
distantly related from commonly used model organisms in cell biology, and thus offers an …