To the Editors, We read the article by Dretler et al. 1 regarding meningococcal disease and
vaccination with great interest. As stated in this review, individuals receiving the complement …

Aims This study compared the aggregate duration of treatment administration of approved
eculizumab and ravulizumab treatment regimens and resultant productivity implications for …

Background Atypical hemolytic uremic syndrome is a rare disorder which is known to cause
acute thrombotic microangiopathy during pregnancy with poor maternal and fetal outcomes …

Background The incidence of gemcitabine-induced hemolytic uremic syndrome has already
been described in adults. Several approaches have been employed in the treatment of …

Background The aim of this study was to investigate the histopathological findings in kidney
biopsies in children with atypical hemolytic uremic syndrome (aHUS) and to determine …

Moraxella lacunata, a low-virulence Gram-negative coccobacillus, is classically associated
with conjunctivitis and upper respiratory tract infections; systemic infections such as sepsis …

2017-09-20 Assigned to ALEXION PHARMACEUTICALS, INC. reassignment ALEXION
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

The disclosure provides antibodies that are useful for, among other things, inhibiting
terminal complement (eg, the assembly and/or activity of the C5b-9 TCC) and C5a …

Related US Application Data Continuation of application No. 15/708,658, filed on Sep. 19,
2017, now Pat. No. 10,227,400, which is a continuation of application No. 15/492,622, filed …

A 6-month-old female infant was referred with a 3-day history of low-grade fever, slight nasal
congestion and rhinorrhoea. On admission, the clinical findings were unremarkable and she …