Simple Summary The IL-12 family cytokines play an important role in regulating the tumor
immune contexture. Recent efforts geared towards the development of better immune …

The incidence of penile squamous cell carcinoma (PSCC) has increased in developed
countries over the past decades owing to increased human papilloma virus (HPV) exposure …

Malignant melanoma is the utmost severe form of skin cancer, causing the vast majority of
deaths related to skin cancer in humans. Although melanoma is treatable at its early stages …

Photoaging and epithelial skin tumorigenesis are complex processes triggered mainly by
UV radiation from chronic sun exposure. This leads to DNA damage and reactive oxygen …

Immunotherapy for skin malignancies has ushered in a new era for cancer treatments by
demonstrating unprecedented durable responses in the setting of metastatic Melanoma …

Oxidative stress and inflammation are important critical factors that are implicated in almost
all life style disorders such as diabetes, cardiovascular disease, ulcer and cancer. Current …

Cancer incidence increases exponentially with age when human telomeres are shorter.
Similarly, telomerase reverse transcriptase (tert) mutant zebrafish have premature short …

Mounting evidence indicates that the microbiota, the unique combination of micro-organisms
residing in a specific environment, plays an essential role in the development of a wide …

Hyperthermia is a cancer treatment where tumor tissue is heated to around 40° C.
Hyperthermia shows both cancer cell cytotoxicity and immune response stimulation via …

Melanoma, an aggressive malignant tumor originating from melanocytes in humans, is on
the rise globally, with limited non-surgical treatment options available. Recent …