Efficacy and safety of direct oral factor Xa inhibitors compared with warfarin in patients with morbid obesity: a single-centre, retrospective analysis of chart data

M Kushnir, Y Choi, R Eisenberg, D Rao… - The Lancet …, 2019 - thelancet.com
Background Because studies of direct oral anticoagulants in patients with venous
thromboembolism and non-valvular atrial fibrillation have had minimal representation of …

Effects of body mass index on the safety and effectiveness of direct oral anticoagulants: a retrospective review

J Netley, K Howard, W Wilson - Journal of Thrombosis and Thrombolysis, 2019 - Springer
Abstract Background The International Society on Thrombosis and Haemostasis
recommends avoiding the use of direct oral anticoagulants (DOACs) in patients with a body …

[HTML][HTML] Review of medical therapies for the management of pulmonary embolism

L Panahi, G Udeani, M Horseman, J Weston, N Samuel… - Medicina, 2021 - mdpi.com
Traditionally, the management of patients with pulmonary embolism has been accomplished
with anticoagulant treatment with parenteral heparins and oral vitamin K antagonists …

[HTML][HTML] Effectiveness and safety of oral anticoagulants among NVAF patients with obesity: insights from the ARISTOPHANES study

S Deitelzweig, A Keshishian, A Kang… - Journal of Clinical …, 2020 - mdpi.com
This ARISTOPHANES analysis examined stroke/systemic embolism (SE) and major
bleeding (MB) among a subgroup of nonvalvular atrial fibrillation (NVAF) patients with …

Evaluation of the efficacy of direct oral anticoagulants (DOACs) in comparison to warfarin in morbidly obese patients

C Kalani, E Awudi, T Alexander, G Udeani… - Hospital …, 2019 - Taylor & Francis
Purpose: There is limited clinical data evaluating anticoagulation with the direct oral
anticoagulants (DOACs) in morbidly obese patients. We sought to examine the efficacy in …

Efficacy and safety of direct‐acting Oral anticoagulants (DOACs) in the overweight and obese

K Doucette, H Latif, A Vakiti, E Tefera… - Advances in …, 2020 - Wiley Online Library
Obesity plays an essential role in the safety of pharmacologic drugs. There is paucity of data
for direct oral anticoagulants (DOACs) in the obese, despite these agents becoming more …

[PDF][PDF] Body weight is negatively associated with direct oral anticoagulant trough concentrations in dabigatran and apixaban users

JM Borst, N van Rein, ECMD Bakker… - British Journal of …, 2020 - repub.eur.nl
Direct oral anticoagulants (DOACs, ie dabigatran, apixaban, edoxaban and rivaroxaban) are
prescribed in fixed-dose regimens to treat and prevent thrombosis. 1 The market …

[HTML][HTML] A new test for the detection of direct oral anticoagulants (Rivaroxaban and Apixaban) in the emergency room setting

GH Frydman, F Ellett, EM Van Cott… - Critical Care …, 2019 - journals.lww.com
Objectives: Determining whether a patient has taken a direct oral anticoagulant (DOAC) is
critical during the periprocedural and preoperative period in the emergency department …

[HTML][HTML] Anticoagulants in the management of pulmonary embolism

L Panahi, G Udeani, M Horseman… - New Knowledge …, 2021 - intechopen.com
Pulmonary embolism management has typically been accomplished with anticoagulant
treatment that includes parenteral heparins and oral vitamin K antagonists. Even though …

Pharmacy student monitoring of direct oral anticoagulants

JJ Kim, HL Hill, JB Groce III… - Journal of …, 2018 - journals.sagepub.com
Background: Best practice recommendations are lacking. Thus far, literature has described
pharmacist-led DOAC monitoring. Objective: The purpose of this study is to describe a …