Knock-on effects of environmental influences during embryonic development of ectothermic vertebrates

B Jonsson, N Jonsson… - The Quarterly Review of …, 2022 - journals.uchicago.edu
Environmental factors influencing parents or offspring during embryogenesis can have
knock-on effects at later life stages of the offspring. These effects may prepare the progeny …

Genetic background of multiple sclerosis

AD Sadovnick - Autoimmunity reviews, 2012 - Elsevier
Multiple sclerosis (MS) is a one of the group of diseases labeled as “common complex”.
Virtually all common complex traits, genetic and environmental components have important …

Epigenetic regulation of EMT in non-small cell lung cancer

K O'Leary, A Shia, P Schmid - Current cancer drug targets, 2018 - ingentaconnect.com
Lung cancer remains the most diagnosed cancer in the world, with a high mortality rate and
fewer therapeutic options. The most common lung cancer is non-small cell, consisting of …

[HTML][HTML] Emerging role of epigenetics in explaining relationship of periodontitis and cardiovascular diseases

SA Hamza, S Asif, Z Khurshid, MS Zafar, SAH Bokhari - Diseases, 2021 - mdpi.com
Cardiovascular diseases such as ischemic heart diseases or stroke are among the leading
cause of deaths globally, and evidence suggests that these diseases are modulated by a …

[HTML][HTML] Epigenetic regulation of adult neural stem cells: implications for Alzheimer's disease

CP Fitzsimons, E Van Bodegraven, M Schouten… - Molecular …, 2014 - Springer
Experimental evidence has demonstrated that several aspects of adult neural stem cells
(NSCs), including their quiescence, proliferation, fate specification and differentiation, are …

Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI

Y Yang, MJ Knol, R Wang, A Mishra, D Liu, M Luciano… - Brain, 2023 - academic.oup.com
Cerebral white matter hyperintensities on MRI are markers of cerebral small vessel disease,
a major risk factor for dementia and stroke. Despite the successful identification of multiple …

Developmental plasticity and epigenetic mechanisms underpinning metabolic and cardiovascular diseases

FM Low, PD Gluckman, MA Hanson - Epigenomics, 2011 - Future Medicine
The importance of developmental factors in influencing the risk of later-life disease has a
strong evidence base derived from multiple epidemiological, clinical and experimental …

Gender issues in multiple sclerosis: an update

C Jobin, C Larochelle, H Parpal, PK Coyle… - Women's …, 2010 - journals.sagepub.com
Although multiple sclerosis (MS) affects both women and men, women are more susceptible
to MS than men. Accumulating evidence indicates that the incidence and prevalence of MS …

[HTML][HTML] Is Lamarckian evolution relevant to medicine?

AE Handel, SV Ramagopalan - BMC medical genetics, 2010 - Springer
Background 200 years have now passed since Darwin was born and scientists around the
world are celebrating this important anniversary of the birth of an evolutionary visionary …

Apoptosis in follicles of individuals with female pattern hair loss is associated with perifollicular microinflammation

PM Ramos, G Brianezi, ACP Martins… - … Journal of Cosmetic …, 2016 - Wiley Online Library
Objective The objective of this study is to evaluate apoptosis in hair follicles of patients with
female pattern hair loss (FPHL) and its association with follicular microinflammation. Method …