Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Mitophagy is a selective autophagic process, essential for cellular homeostasis, that
eliminates dysfunctional mitochondria. Activated by inner membrane depolarization, it plays …

Association of diabetes with an elevated risk of cardiac failure has been clinically evident.
Diabetes potentiates diastolic and systolic cardiac failure following the myocardial infarction …

A large body of evidence indicates the existence of a complex pathophysiological
relationship between cardiovascular diseases and cancer. Mitochondria are crucial …

Increasing evidence indicates the involvement of myocardial oxidative injury and
mitochondrial dysfunction in the pathophysiology of heart failure (HF). Alpha-ketoglutarate …

Cardiac hypertrophy is frequently associated with ventricular dysfunction and heart failure.
Paeoniflorin, has been widely used to treat cardiovascular dysfunction-related diseases …

Cardiovascular disease (CVD) is one of the predominant causes of death and morbidity.
Mitochondria play a key role in maintaining cardiac energy metabolism. However …

Geroscience posits that cardiovascular disease (CVD) and other chronic diseases result
from progressive erosion of the effectiveness of homeostatic mechanisms that oppose age …

Cardiovascular diseases (CVD), with high morbidity and mortality, seriously affect people's
life and social development. Clinically, reperfusion therapy is typically used to treat ischemic …

The myocardium is among the most energy-consuming tissues in the body, burning from 6 to
30 kg of ATP per day within the mitochondria, the so-called powerhouse of the …