[HTML][HTML] Recent progress in drug delivery

C Li, J Wang, Y Wang, H Gao, G Wei, Y Huang… - … pharmaceutica sinica B, 2019 - Elsevier
Drug delivery systems (DDS) are defined as methods by which drugs are delivered to
desired tissues, organs, cells and subcellular organs for drug release and absorption …

[HTML][HTML] Antibacterial prodrugs to overcome bacterial resistance

B Jubeh, Z Breijyeh, R Karaman - Molecules, 2020 - mdpi.com
Bacterial resistance to present antibiotics is emerging at a high pace that makes the
development of new treatments a must. At the same time, the development of novel …

[HTML][HTML] Advanced applications of DNA nanostructures dominated by DNA origami in antitumor drug delivery

Y Zhang, X Tian, Z Wang, H Wang, F Liu… - Frontiers in Molecular …, 2023 - frontiersin.org
DNA origami is a cutting-edge DNA self-assembly technique that neatly folds DNA strands
and creates specific structures based on the complementary base pairing principle. These …

Drug screening of rhodanine derivatives for antibacterial activity

S Maddila, S Gorle… - Expert Opinion on Drug …, 2020 - Taylor & Francis
Introduction: Bacteriological infections are a major risk to human health. These include all
hospital and public-acquired infections. In drug discovery, rhodanines are privileged …

[HTML][HTML] Advanced prodrug strategies in nucleoside and non-nucleoside antiviral agents: A review of the recent five years

H Sinokrot, T Smerat, A Najjar, R Karaman - Molecules, 2017 - mdpi.com
Background: Poor pharmacokinetic profiles and resistance are the main two drawbacks from
which currently used antiviral agents suffer, thus make them excellent targets for research …

Harnessing mesenchymal stem cell homing as an anticancer therapy

A Hagenhoff, CJ Bruns, Y Zhao… - Expert opinion on …, 2016 - Taylor & Francis
ABSTRACT Introduction: Mesenchymal stromal cells (MSCs) are non-hematopoietic
progenitor cells that have been exploited as vehicles for cell-based cancer therapy. The …

[HTML][HTML] Strategies for the development of stimuli-responsive small molecule prodrugs for cancer treatment

Y Tu, J Gong, J Mou, H Jiang, H Zhao… - Frontiers in …, 2024 - frontiersin.org
Approved anticancer drugs typically face challenges due to their narrow therapeutic window,
primarily because of high systemic toxicity and limited selectivity for tumors. Prodrugs are …

[HTML][HTML] Human Serum Albumin Labelling with a New BODIPY Dye Having a Large Stokes Shift

VI Raskolupova, TV Popova, OD Zakharova… - Molecules, 2021 - mdpi.com
BODIPY dyes are photostable neutral derivatives of 4, 4-difluoro-4-bora-3a, 4a-diaza-s-
indacene. These are widely used as chemosensors, laser materials, and molecular probes …

Improving the pharmacokinetics and tissue distribution of pyrinezolid by self-assembled polymeric micelles

H Long, X Li, Z Sang, L Mei, T Yang, Z Li, L Zhou… - Colloids and Surfaces B …, 2017 - Elsevier
Antibiotic-resistance by bacteria is a growing global concern within the healthcare field, and
it has provided an impetus for continued antimicrobial development. Pyrinezolid (PZ), a …

Intelligent self-assembly prodrug micelles loading doxorubicin in response to tumor microenvironment for targeted tumors therapy

D Wan, S Li, J Zhang, G Ma, J Pan - Chinese Journal of Chemical …, 2021 - Elsevier
Compared with physical drug-loaded nanocarriers, polymeric prodrug micelles have many
advantages such as high drug loading and enhanced stability in blood, so they have great …