Towards network-guided neuromodulation for epilepsy
Epilepsy is well-recognized as a disorder of brain networks. There is a growing body of
research to identify critical nodes within dynamic epileptic networks with the aim to target …
research to identify critical nodes within dynamic epileptic networks with the aim to target …
[HTML][HTML] Insights and opportunities for deep brain stimulation as a brain circuit intervention
Deep brain stimulation (DBS) is an effective treatment and has provided unique insights into
the dynamic circuit architecture of brain disorders. This Review illustrates our current …
the dynamic circuit architecture of brain disorders. This Review illustrates our current …
The future of brain circuit-targeted therapeutics
The principle of targeting brain circuits has drawn increasing attention with the growth of
brain stimulation treatments such as transcranial magnetic stimulation (TMS), deep brain …
brain stimulation treatments such as transcranial magnetic stimulation (TMS), deep brain …
Challenges and opportunities of implantable neural interfaces: From material, electrochemical and biological perspectives
Q Zeng, Z Huang - Advanced Functional Materials, 2023 - Wiley Online Library
The desirable implantable neural interfaces can accurately record bioelectrical signals from
neurons and regulate neural activities with high spatial/time resolution, facilitating the …
neurons and regulate neural activities with high spatial/time resolution, facilitating the …
[HTML][HTML] Mapping dysfunctional circuits in the frontal cortex using deep brain stimulation
B Hollunder, JL Ostrem, IA Sahin, N Rajamani… - Nature …, 2024 - nature.com
Frontal circuits play a critical role in motor, cognitive and affective processing, and their
dysfunction may result in a variety of brain disorders. However, exactly which frontal …
dysfunction may result in a variety of brain disorders. However, exactly which frontal …
[HTML][HTML] Automated deep brain stimulation programming based on electrode location: a randomised, crossover trial using a data-driven algorithm
Background Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is highly
effective in controlling motor symptoms in patients with Parkinson's disease. However …
effective in controlling motor symptoms in patients with Parkinson's disease. However …
[HTML][HTML] Head movement dynamics in dystonia: a multi-centre retrospective study using visual perceptive deep learning
R Peach, M Friedrich, L Fronemann… - npj Digital …, 2024 - nature.com
Dystonia is a neurological movement disorder characterised by abnormal involuntary
movements and postures, particularly affecting the head and neck. However, current clinical …
movements and postures, particularly affecting the head and neck. However, current clinical …
[HTML][HTML] Elevating the field for applying neuroimaging to individual patients in psychiatry
Although neuroimaging has been widely applied in psychiatry, much of the exuberance in
decades past has been tempered by failed replications and a lack of definitive evidence to …
decades past has been tempered by failed replications and a lack of definitive evidence to …
[PDF][PDF] The intralaminar thalamus: a review of its role as a target in functional neurosurgery
H Arnts, SE Coolen, FW Fernandes… - Brain …, 2023 - academic.oup.com
The intralaminar thalamus, in particular the centromedian-parafascicular complex, forms a
strategic node between ascending information from the spinal cord and brainstem and …
strategic node between ascending information from the spinal cord and brainstem and …
Programming of subthalamic nucleus deep brain stimulation with hyperdirect pathway and corticospinal tract‐guided parameter suggestions
A Segura‐Amil, A Nowacki, I Debove… - Human brain …, 2023 - Wiley Online Library
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for
advanced Parkinson's disease. Stimulation of the hyperdirect pathway (HDP) may mediate …
advanced Parkinson's disease. Stimulation of the hyperdirect pathway (HDP) may mediate …