Towards network-guided neuromodulation for epilepsy

RJ Piper, RM Richardson, G Worrell, DW Carmichael… - Brain, 2022 - academic.oup.com
Epilepsy is well-recognized as a disorder of brain networks. There is a growing body of
research to identify critical nodes within dynamic epileptic networks with the aim to target …

[HTML][HTML] Insights and opportunities for deep brain stimulation as a brain circuit intervention

WJ Neumann, A Horn, AA Kühn - Trends in Neurosciences, 2023 - cell.com
Deep brain stimulation (DBS) is an effective treatment and has provided unique insights into
the dynamic circuit architecture of brain disorders. This Review illustrates our current …

The future of brain circuit-targeted therapeutics

SH Siddiqi, S Khosravani, JD Rolston… - …, 2024 - nature.com
The principle of targeting brain circuits has drawn increasing attention with the growth of
brain stimulation treatments such as transcranial magnetic stimulation (TMS), deep brain …

Challenges and opportunities of implantable neural interfaces: From material, electrochemical and biological perspectives

Q Zeng, Z Huang - Advanced Functional Materials, 2023 - Wiley Online Library
The desirable implantable neural interfaces can accurately record bioelectrical signals from
neurons and regulate neural activities with high spatial/time resolution, facilitating the …

[HTML][HTML] Mapping dysfunctional circuits in the frontal cortex using deep brain stimulation

B Hollunder, JL Ostrem, IA Sahin, N Rajamani… - Nature …, 2024 - nature.com
Frontal circuits play a critical role in motor, cognitive and affective processing, and their
dysfunction may result in a variety of brain disorders. However, exactly which frontal …

[HTML][HTML] Automated deep brain stimulation programming based on electrode location: a randomised, crossover trial using a data-driven algorithm

J Roediger, TA Dembek, J Achtzehn… - The Lancet Digital …, 2023 - thelancet.com
Background Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is highly
effective in controlling motor symptoms in patients with Parkinson's disease. However …

[HTML][HTML] Head movement dynamics in dystonia: a multi-centre retrospective study using visual perceptive deep learning

R Peach, M Friedrich, L Fronemann… - npj Digital …, 2024 - nature.com
Dystonia is a neurological movement disorder characterised by abnormal involuntary
movements and postures, particularly affecting the head and neck. However, current clinical …

[HTML][HTML] Elevating the field for applying neuroimaging to individual patients in psychiatry

DR Roalf, M Figee, DJ Oathes - Translational Psychiatry, 2024 - nature.com
Although neuroimaging has been widely applied in psychiatry, much of the exuberance in
decades past has been tempered by failed replications and a lack of definitive evidence to …

[PDF][PDF] The intralaminar thalamus: a review of its role as a target in functional neurosurgery

H Arnts, SE Coolen, FW Fernandes… - Brain …, 2023 - academic.oup.com
The intralaminar thalamus, in particular the centromedian-parafascicular complex, forms a
strategic node between ascending information from the spinal cord and brainstem and …

Programming of subthalamic nucleus deep brain stimulation with hyperdirect pathway and corticospinal tract‐guided parameter suggestions

A Segura‐Amil, A Nowacki, I Debove… - Human brain …, 2023 - Wiley Online Library
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for
advanced Parkinson's disease. Stimulation of the hyperdirect pathway (HDP) may mediate …