[HTML][HTML] The role of macrophage ion channels in the progression of atherosclerosis

X Wu, S Singla, JJ Liu, L Hong - Frontiers in Immunology, 2023 - frontiersin.org
Atherosclerosis is a complex inflammatory disease that affects the arteries and can lead to
severe complications such as heart attack and stroke. Macrophages, a type of immune cell …

[HTML][HTML] Voltage-Gated Proton Channels in the Tree of Life

G Chaves, C Jardin, C Derst, B Musset - Biomolecules, 2023 - mdpi.com
With a single gene encoding HV1 channel, proton channel diversity is particularly low in
mammals compared to other members of the superfamily of voltage-gated ion channels …

[HTML][HTML] Mechanically-primed voltage-gated proton channels from angiosperm plants

C Zhao, PD Webster, A De Angeli… - Nature Communications, 2023 - nature.com
Voltage-gated and mechanically-gated ion channels are distinct classes of membrane
proteins that conduct ions across gated pores and are turned on by electrical or mechanical …

[HTML][HTML] Trp207 regulation of voltage-dependent activation of human Hv1 proton channel

L Zhang, X Wu, X Cao, K Rao, L Hong - Journal of Biological Chemistry, 2024 - ASBMB
In voltage-gated Na+ and K+ channels, the hydrophobicity of non-charged residues in the
S4 helix has been shown to regulate the S4 movement underlying the process of voltage …

Activation-pathway transitions in human voltage-gated proton channels revealed by a non-canonical fluorescent amino acid

E Suárez-Delgado, M Orozco-Contreras… - Elife, 2023 - elifesciences.org
Voltage-dependent gating of the voltage-gated proton channels (HV 1) remains poorly
understood, partly because of the difficulty of obtaining direct measurements of voltage …

Proton channels in molluscs: A new bivalvian‐specific minimal HV4 channel

G Chaves, C Jardin, A Franzen, I Mahorivska… - The FEBS …, 2023 - Wiley Online Library
Recently, three proton channels (HV) have been identified and characterized in Aplysia
californica (AcHV1‐3). Focusing on AcHV1 and AcHV2, analysis of Transcriptome Shotgun …