[HTML][HTML] Hepatic stellate cell-immune interactions in NASH

JK Carter, SL Friedman - Frontiers in Endocrinology, 2022 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) is the dominant cause of liver disease worldwide.
Nonalcoholic steatohepatitis (NASH), a more aggressive presentation of NAFLD, is …

[HTML][HTML] The evolving role of immune checkpoint inhibitors in hepatocellular carcinoma treatment

P Leone, AG Solimando, R Fasano, A Argentiero… - Vaccines, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is one of most common cancers and the fourth leading
cause of death worldwide. Commonly, HCC development occurs in a liver that is severely …

[HTML][HTML] 2016 comprehensive update of the Banff working group on liver allograft pathology: introduction of antibody-mediated rejection

AJ Demetris, C Bellamy, SG Hübscher, J O'leary… - American Journal of …, 2016 - Elsevier
The Banff Working Group on Liver Allograft Pathology reviewed and discussed literature
evidence regarding antibody-mediated liver allograft rejection at the 11th (Paris, France …

Understanding, predicting and achieving liver transplant tolerance: from bench to bedside

AW Thomson, J Vionnet… - Nature Reviews …, 2020 - nature.com
In the past 40 years, liver transplantation has evolved from a high-risk procedure to one that
offers high success rates for reversal of liver dysfunction and excellent patient and graft …

[HTML][HTML] Hepatic stellate cells: dictating outcome in nonalcoholic fatty liver disease

L Wiering, P Subramanian, L Hammerich - Cellular and Molecular …, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a fast growing, chronic liver disease affecting∼
25% of the global population. Nonalcoholic fatty liver disease severity ranges from the less …

Crosstalk between hepatic stellate cells and surrounding cells in hepatic fibrosis

F Yang, H Li, Y Li, Y Hao, C Wang, P Jia, X Chen… - International …, 2021 - Elsevier
Hepatic fibrosis represents as a dynamic pathological process characterized by the net
accumulation of extracellular matrix in the progression of various chronic liver diseases …

Activated hepatic stellate cells regulate MDSC migration through the SDF-1/CXCR4 axis in an orthotopic mouse model of hepatocellular carcinoma

Y Xu, F Fang, H Jiao, X Zheng, L Huang, X Yi… - Cancer Immunology …, 2019 - Springer
Hepatic stellate cells (HSCs) are important stromal cells and pivotal mediators involved in
the pathogenesis and immunosuppression of hepatocellular carcinoma (HCC). The liver has …

[HTML][HTML] Interorgan communication with the liver: novel mechanisms and therapeutic targets

J Zhao, X Zhang, Y Li, J Yu, Z Chen, Y Niu… - Frontiers in …, 2023 - frontiersin.org
The liver is a multifunctional organ that plays crucial roles in numerous physiological
processes, such as production of bile and proteins for blood plasma, regulation of blood …

[HTML][HTML] B cells induced by Schistosoma japonicum infection display diverse regulatory phenotypes and modulate CD4+ T cell response

J Xiao, F Guan, L Sun, Y Zhang, X Zhang, S Lu… - Parasites & vectors, 2020 - Springer
Background The increased activity of regulatory B cells (Breg) is known to be involved in
immunosuppression during helminth infection, which is characterized by inducing IL-10 …

DNA damage response and PD-1/PD-L1 pathway in ovarian cancer

T Zhang, S Zheng, Y Liu, X Li, J Wu, Y Sun, G Liu - DNA repair, 2021 - Elsevier
Ovarian cancer has a poor prognosis due to drug resistance, relapse and metastasis. In
recent years, immunotherapy has been applied in numerous cancers clinically. However …