Real‐time PCR is a recent modification to the polymerase chain reaction that allows precise
quantification of specific nucleic acids in a complex mixture by fluorescent detection of …

Background New diagnostic tools for malaria are required owing to the changing
epidemiology of malaria, particularly among pregnant women in sub-Saharan Africa. Real …

Drug-resistant Plasmodium falciparum is a challenge to malaria control programs. Policy
makers currently depend on in vivo (and, sometimes, in vitro) resistance testing to set …

Real‐time PCR is a recent modification to the polymerase chain reaction that allows precise
quantification of specific nucleic acids in a complex mixture by fluorescent detection of …

Background Resistance to sulphadoxine-pyrimethamine (SP) in Plasmodium falciparum
parasites is associated with mutations in the dihydrofolate reductase (dhfr) and …

The emergence of Plasmodium falciparum resistance to artemisinin in Southeast Asia
threatens malaria control and elimination activities worldwide. Multiple polymorphisms in the …

Trypanosome lytic factor 1 (TLF1) is a subclass of human high-density lipoprotein that kills
some African trypanosomes thereby protecting humans from infection. We have shown that …

Objective New anti-malarial regimens are urgently needed in sub-Saharan Africa because
of the increase in drug resistance. We investigated the safety and efficacy of azithromycin or …

Malaria is an infectious disease transmitted by the female Anopheles mosquito and poses a
severe threat to human health. At present, antimalarial drugs are the primary treatment for …

Objective To determine the relationship between mutations in dhfr and dhps and SP
treatment failure in Plasmodium falciparum malaria in the Democratic Republic of the Congo …