Ferroptosis: a new regulatory mechanism in osteoporosis

P Liu, W Wang, Z Li, Y Li, X Yu, J Tu… - Oxidative Medicine and …, 2022 - Wiley Online Library
Osteoporosis can be caused by a multitude of factors and is defined by a decrease in bone
density and mass caused by the destruction of bone microstructure, resulting in increased …

[HTML][HTML] Mechanisms of ferroptosis and emerging links to the pathology of neurodegenerative diseases

Y Sun, X Xia, D Basnet, JC Zheng… - Frontiers in aging …, 2022 - frontiersin.org
Neurodegenerative diseases are a diverse class of diseases attributed to chronic
progressive neuronal degeneration and synaptic loss in the brain and/or spinal cord …

High level of uric acid promotes atherosclerosis by targeting NRF2‐Mediated autophagy dysfunction and ferroptosis

W Yu, W Liu, D Xie, Q Wang, C Xu… - Oxidative Medicine …, 2022 - Wiley Online Library
Atherosclerotic vascular disease (ASVD) is the leading cause of death worldwide.
Hyperuricemia is the fourth risk factor for atherosclerosis after hypertension, diabetes, and …

Salidroside inhibits doxorubicin-induced cardiomyopathy by modulating a ferroptosis-dependent pathway

H Chen, J Zhu, Y Le, J Pan, Y Liu, Z Liu, C Wang… - Phytomedicine, 2022 - Elsevier
Background Doxorubicin-induced cardiotoxicity (DIC) limits the clinical application of the
drug in treatment of cancers and imposes a severe health burden on the patients. Therefore …

[HTML][HTML] The mechanism of ferroptosis regulating oxidative stress in ischemic stroke and the regulation mechanism of natural pharmacological active components

K Yang, L Zeng, X Yuan, S Wang, A Ge, H Xu… - Biomedicine & …, 2022 - Elsevier
Cerebrovascular diseases, such as ischemic stroke, pose serious medical challenges
worldwide due to their high morbidity and mortality and limitations in clinical treatment …

[HTML][HTML] Macrophage subsets and death are responsible for atherosclerotic plaque formation

H Li, Z Cao, L Wang, C Liu, H Lin, Y Tang… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular diseases, the notorious killer, are mainly caused by atherosclerosis (AS)
characterized by lipids, cholesterol, and iron overload in plaques. Macrophages are effector …

Myocardial ischemia-reperfusion injury; Molecular mechanisms and prevention

Y Liu, L Li, Z Wang, J Zhang, Z Zhou - Microvascular Research, 2023 - Elsevier
Cardiovascular diseases are one of the leading causes of mortality in developed countries.
Among cardiovascular disorders, myocardial infarction remains a life-threatening problem …

[HTML][HTML] ENO3 promoted the progression of NASH by negatively regulating ferroptosis via elevation of GPX4 expression and lipid accumulation

D Lu, Q Xia, Z Yang, S Gao, S Sun, X Luo… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background ENO3 expression is upregulated in Non-alcoholic fatty liver disease (NAFLD)
patient tissues, demonstrated that ENO3 might play crucial roles in NAFLD. However, the …

[HTML][HTML] Role of PKM2-mediated immunometabolic reprogramming on development of cytokine storm

Z Liu, Y Le, H Chen, J Zhu, D Lu - Frontiers in immunology, 2021 - frontiersin.org
The cytokine storm is a marker of severity of various diseases and increased mortality. The
altered metabolic profile and energy generation of immune cells affects their activation …

[HTML][HTML] Potential intervention target of atherosclerosis: Ferroptosis

J Li, L Xu, YX Zuo, XQ Chang… - Molecular Medicine …, 2022 - spandidos-publications.com
Atherosclerosis (AS) is a chronic inflammatory disease of the blood vessels, which is mainly
characterized by the form of atherosclerotic plaques and vascular endothelial injury. Its …