Ferroptosis: a new regulatory mechanism in osteoporosis
P Liu, W Wang, Z Li, Y Li, X Yu, J Tu… - Oxidative Medicine and …, 2022 - Wiley Online Library
Osteoporosis can be caused by a multitude of factors and is defined by a decrease in bone
density and mass caused by the destruction of bone microstructure, resulting in increased …
density and mass caused by the destruction of bone microstructure, resulting in increased …
[HTML][HTML] Mechanisms of ferroptosis and emerging links to the pathology of neurodegenerative diseases
Neurodegenerative diseases are a diverse class of diseases attributed to chronic
progressive neuronal degeneration and synaptic loss in the brain and/or spinal cord …
progressive neuronal degeneration and synaptic loss in the brain and/or spinal cord …
High level of uric acid promotes atherosclerosis by targeting NRF2‐Mediated autophagy dysfunction and ferroptosis
Atherosclerotic vascular disease (ASVD) is the leading cause of death worldwide.
Hyperuricemia is the fourth risk factor for atherosclerosis after hypertension, diabetes, and …
Hyperuricemia is the fourth risk factor for atherosclerosis after hypertension, diabetes, and …
Salidroside inhibits doxorubicin-induced cardiomyopathy by modulating a ferroptosis-dependent pathway
H Chen, J Zhu, Y Le, J Pan, Y Liu, Z Liu, C Wang… - Phytomedicine, 2022 - Elsevier
Background Doxorubicin-induced cardiotoxicity (DIC) limits the clinical application of the
drug in treatment of cancers and imposes a severe health burden on the patients. Therefore …
drug in treatment of cancers and imposes a severe health burden on the patients. Therefore …
[HTML][HTML] The mechanism of ferroptosis regulating oxidative stress in ischemic stroke and the regulation mechanism of natural pharmacological active components
K Yang, L Zeng, X Yuan, S Wang, A Ge, H Xu… - Biomedicine & …, 2022 - Elsevier
Cerebrovascular diseases, such as ischemic stroke, pose serious medical challenges
worldwide due to their high morbidity and mortality and limitations in clinical treatment …
worldwide due to their high morbidity and mortality and limitations in clinical treatment …
[HTML][HTML] Macrophage subsets and death are responsible for atherosclerotic plaque formation
H Li, Z Cao, L Wang, C Liu, H Lin, Y Tang… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular diseases, the notorious killer, are mainly caused by atherosclerosis (AS)
characterized by lipids, cholesterol, and iron overload in plaques. Macrophages are effector …
characterized by lipids, cholesterol, and iron overload in plaques. Macrophages are effector …
Myocardial ischemia-reperfusion injury; Molecular mechanisms and prevention
Y Liu, L Li, Z Wang, J Zhang, Z Zhou - Microvascular Research, 2023 - Elsevier
Cardiovascular diseases are one of the leading causes of mortality in developed countries.
Among cardiovascular disorders, myocardial infarction remains a life-threatening problem …
Among cardiovascular disorders, myocardial infarction remains a life-threatening problem …
[HTML][HTML] ENO3 promoted the progression of NASH by negatively regulating ferroptosis via elevation of GPX4 expression and lipid accumulation
D Lu, Q Xia, Z Yang, S Gao, S Sun, X Luo… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background ENO3 expression is upregulated in Non-alcoholic fatty liver disease (NAFLD)
patient tissues, demonstrated that ENO3 might play crucial roles in NAFLD. However, the …
patient tissues, demonstrated that ENO3 might play crucial roles in NAFLD. However, the …
[HTML][HTML] Role of PKM2-mediated immunometabolic reprogramming on development of cytokine storm
Z Liu, Y Le, H Chen, J Zhu, D Lu - Frontiers in immunology, 2021 - frontiersin.org
The cytokine storm is a marker of severity of various diseases and increased mortality. The
altered metabolic profile and energy generation of immune cells affects their activation …
altered metabolic profile and energy generation of immune cells affects their activation …
[HTML][HTML] Potential intervention target of atherosclerosis: Ferroptosis
J Li, L Xu, YX Zuo, XQ Chang… - Molecular Medicine …, 2022 - spandidos-publications.com
Atherosclerosis (AS) is a chronic inflammatory disease of the blood vessels, which is mainly
characterized by the form of atherosclerotic plaques and vascular endothelial injury. Its …
characterized by the form of atherosclerotic plaques and vascular endothelial injury. Its …